Recombinant Human BMP-2 Protein(Gst Tag)
| Specifications | |
|---|---|
| Molecular Weight: | 38 kDa |
| Tag: | N-Gst |
| Source: | E.coli |
| Purity: | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 1.0 EU per μg of the protein as determined by the LAL method |
| Format: | Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol. |
| Additional Information | |
|---|---|
| Synonyms: | BDA2;BMP-2;BMP-2A;Bmp2;BMP2;BMP2A;Bone morphogenetic protein 2;Bone morphogenetic protein 2A |
| Organism: | Human |
| Accn. No.: | P12643 |
Sequence Information
Gln283-Arg396
Background
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients.
Price
284,00 €
