Human IL-1 RAcP / IL-1 R3 Protein
Specifications | |
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Category: | Cytokines&Growth Factors |
Molecular Weight: | 40.2 kDa |
Tag: | C-8×His |
Label / Conjugate: | N/A |
Source: | Human IL-1 RAcP, His Tag (ILP-H5225) is expressed from human 293 cells (HEK293). It contains AA Ser 21 - Glu 359 (Accession # Q9NPH3). |
Purity: | 95% |
Endotoxin Level: | 1.0 EU per μg |
Format: | Powder |
Additional Information | |
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Synonyms: | IL1RAP,IL-1RAcP,C3orf13,IL1R3 |
Organism: | Human |
Accn. No.: | Q9NPH3 |
Sequence Information
Ser 21 - Glu 359
Background
Interleukin-1 receptor accessory protein (IL1RAP or IL-1RAcP) is also known as Interleukin-1 receptor 3 (IL-1R-3 or IL-1R3), C3orf13, which belongs to the interleukin-1 receptor family. IL1RAP contains three Ig-like C2-type (immunoglobulin-like) domains and one TIR domain. IL1RAP is detected in liver, skin, placenta, thymus and lung. IL-1R3 / IL1RAP is coreceptor with IL1R1, associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
Price
296,00 €