Human IL-12 R beta 1 / CD212 Protein, His Tag
| Specifications | |
|---|---|
| Category: | Bio-Markers & CD Antigens |
| Molecular Weight: | 59.0 kDa |
| Tag: | C-10×His |
| Label / Conjugate: | N/A |
| Source: | Human IL-12 R beta 1, His Tag (ILB-H52H9) is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Glu 540 (Accession # P42701-1). |
| Purity: | 90% |
| Endotoxin Level: | 1.0 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | IL-12 R beta 1,IL12RB1,CD212,IL12R,IL12RB,IL-12RB1 |
| Organism: | Human |
| Accn. No.: | P42701-1 |
Sequence Information
Cys 24 - Glu 540
Background
The human IL-12 R subunit is a member of the cytokine receptor superfamily and the functional high-affinity IL-12R is composed of at least two beta-type cytokine receptor subunits, each independently exhibiting a low affinity for IL-12. IL-12 R beta 1 (Interleukin-12 receptor subunit beta-1) is also known as IL-12RB1, CD212. Functions as an interleukin receptor which binds interleukin-12 with low affinity and is involved in IL12 transduction. Associated with IL12RB2 it forms a functional, high affinity receptor for IL12. Associates also with IL23R to form the interleukin-23 receptor which functions in IL23 signal transduction probably through activation of the Jak-Stat signaling cascade.
Price
2.380,00 €
