VitroGel® YIGSR Cell Invasion Assay Kit

Tunable High-Concentration Cell Invasion Assay

Product Description

• Full Control of ECM properties – Unlock the understanding of key ECM factors on cell migration/invasion. Gain new knowledge that was not capable with animal-based ECM)
• Synthetic hydrogel with batch-to-batch consistency: Accurate and reproducible results
• Easy to use at room temperature operation: Supports lab automation and high-throughput applications

Cell invasion, a vital process in various biological contexts, can be pivotal in embryonic development, immunosurveillance, and wound healing while also playing a concerning role in cancer metastasis. Traditional in vitro invasion assays have relied on animal-based extracellular matrices, which come with challenges like undefined components, batch-to-batch variability, and cumbersome temperature-sensitive protocols, thus leading to inconsistent and inaccurate studies.

This VitroGel YIGSR Cell Invasion Assay Kit is powered by VitroGel® hydrogel (versatile, xeno-free, bio-functional hydrogel that closely mimics the physiological extracellular matrix) and coupled with premium quality VitroPrime™ Cell Culture Inserts, allowing more accurate and consistent invasion and migration studies than animal-based ECM. 

The complete range of kits consists of one ready-to-use VitroGel® Cell Invasion Assay Kit (which includes VitroGel Hydrogel Matrix) for traditional cell invasion assay studies and different VitroGel “High Concentration” Cell Invasion Assay Kits where the biophysical and biochemical properties are tunable, allowing researchers to explore how different matrix strengths, ligands, chemokines, growth factors, and more influence cell invasion.

How it works

Work confidently at room temperature. No ice bucket here.  VitroGel Cell Invasion Assay Kit is ready-to-use.  Just mix with your cells.  There is no cross-linking agent required. (Click to learn how gelation works)

Comparison to traditional animal-based ECM