Human GITR / TNFRSF18 Protein
| Specifications | |
|---|---|
| Category: | Immune Checkpoint Proteins |
| Molecular Weight: | 16.4 kDa |
| Tag: | C-6×His |
| Label / Conjugate: | N/A |
| Source: | Human GITR, His Tag (GIR-H5228) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Glu 161 (Accession # Q9Y5U5-1). |
| Purity: | 92% |
| Endotoxin Level: | 1.0 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | AITR,GITR,TNFRSF18,CD357 |
| Organism: | Human |
| Accn. No.: | Q9Y5U5-1 |
Sequence Information
Gln 26 - Glu 161
Background
Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.
Price
3.219,00 €
