Human CD163 Protein
| Specifications | |
|---|---|
| Category: | Bio-Markers & CD Antigens |
| Molecular Weight: | 110.4 kDa |
| Tag: | C-10×His |
| Label / Conjugate: | N/A |
| Source: | Human CD163, His Tag (CD3-H52E8) is expressed from human 293 cells (HEK293). It contains AA Ser 42 - Ser 1045 (Accession # Q86VB7). |
| Purity: | 95% |
| Endotoxin Level: | 1.0 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | CD163,M130 |
| Organism: | Human |
| Accn. No.: | Q86VB7 |
Sequence Information
Ser 42 - Ser 1045
Background
Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is also known as hemoglobin scavenger receptor, which is a scavenger receptor for the hemoglobin-haptoglobin complex. CD163 has also been shown to mark cells of monocyte/macrophage lineage. A soluble form of the receptor exists in plasma, commonly denoted sCD163. sCD163 is generated by ectodomain shedding of the membrane bound receptor. sCD163 is upregulated in a large range of inflammatory diseases including liver cirrhosis, type 2 diabetes, macrophage activation syndrome, Gaucher's disease, sepsis, HIV infection, rheumatoid arthritis and Hodgkin Lymphoma.
Price
3.245,00 €
