Biotinylated Human B7-H3 / CD276 Protein, Fc Tag, Avi Tag (Avitag™)
| Specifications | |
|---|---|
| Category: | MABSol® Biotin Labeled Proteins |
| Molecular Weight: | 51.6 kDa |
| Tag: | C-Fc & C-Avi |
| Label / Conjugate: | Biotin-labeled |
| Source: | Biotinylated Human B7-H3 Protein, Fc,Avitag (B73-H82F5) is expressed from human 293 cells (HEK293). It contains AA Leu 29 - Pro 245 (Accession # Q5ZPR3-2). |
| Purity: | 95% |
| Endotoxin Level: | 1.0 EU per μg |
| Format: | Powder |
| Additional Information | |
|---|---|
| Synonyms: | B7-H3,CD276,B7 homolog 3 |
| Organism: | Human |
| Accn. No.: | Q5ZPR3-2 |
Sequence Information
Leu 29 - Pro 245
Background
B7 homolog 3 (B7-H3), a member of the immunoglobulin superfamily, is also known CD276, which contains two Ig-like C2-type (immunoglobulin-like) domains and two Ig-like V-type (immunoglobulin-like) domains. B7-H3 may participate in the regulation of T-cell-mediated immune response. B7-H3 also plays a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. Furthermore, B7-H3 is involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. It could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy.
Price
505,00 €
