Human EGFR Phosphorylation Array C1
| Specifications | |
|---|---|
| Product Category: | EGFR Phosphorylation Arrays |
| Array Type: | C-Series |
| Semi- / Quantitative: | Semi-Quantitative |
| Solid Support: | Membrane |
| Design Principle: | Sandwich-based |
| Detection Method: | Chemiluminescence |
| Organism: | Human |
| Number of targets: | 17 |
RayBio® C-Series Human EGFR Phosphorylation Antibody Array 1 Kit. Detects 17 site specific and pan Human EGFRs. Suitable for all liquid sample types but intended for use with cell and tissue lysates.
Compatible Sample Types
Cell Culture Supernatants, Plasma, Serum, Tissue Lysates, Cell Lysates
Target Names
EGFR (P-Tyr845), EGFR (P-Tyr992), EGFR (P-Tyr1045), EGFR (P-Tyr1068), EGFR (P-Tyr1086), EGFR (P-Tyr1148), EGFR (P-Tyr1173), EGFR (P-Ser1046/1047), EGFR (P-Ser1070), ErbB2 (P-Tyr877), ErbB2 (P-Tyr1112), ErbB2 (P-Tyr 1221/1222), ErbB2 (P-Tyr1248), ErbB2 (P-Thr686), ErbB2 (P-Ser1113), ErbB3 (P-Tyr1289), ErbB4 (P-Tyr1284)
Pathways Involved
HER/ErbB Signaling
Features
- Easy to use
- No specialized equipment needed
- Compatible with nearly any liquid sample
- Proven technology (many publications)
- Highly sensitive (pg/ml)
- Sandwich ELISA specificity
- Higher density than ELISA, Western blot or bead-based multiplex
Applications
Multiplexed Protein Detection; Detection of Relative Protein Expression; Detecting Patterns of Cytokine Expression; Biomarker/ Key Factor Screening; Identifying Key Factors; Confirming a Biological Process
Free Antibody Array Analysis Tool & Array Scanning Service
All RayBio antibody array kits are supported by a free Excel-based analysis tool particular to each array for the automatic computation of the extracted numerical data obtained from the array image. Features include automated sorting and averaging, background subtraction, normalization, data plotting as well as advanced computations for quantitative arrays. Also antibody lists, array maps and .gal files with the individual layout of each array are available.
In case you do not have access to a compatible laser scanner a scanning service for all RayBio glass slide antibody arrays can be offered for free. Only shipping charges apply.
Please contact us by email, phone or using this form for further details.
Product Citations
- (2020) Giagulli C, Caccuri F, Zorzan S, Bugatti A, Zani A, Filippini F, Manocha E, D'Ursi P, Orro A, Dolcetti R, Caruso A. B-cell clonogenic activity of HIV-1 p17 variants is driven by PAR1-mediated EGF transactivation. Cancer Gene Ther. 2020 Oct 22. doi: 10.1038/s41417-020-00246-9. Epub ahead of print. PMID: 33093643.
- (2018) Ruiz-Saenz A., Dreyer C., Campbell M., et al. HER2 amplification in tumors activates PI3K/Akt signaling independent of HER3. Cancer Research, epub online 2018, doi: 10.1158/0008-5472.CAN-18-0430
- (2018) Tang Q., Wang Y., Ma L., et al. Peiminine serves as an adriamycin chemosensitizer in gastric cancer by modulating the EGFR/FAK pathway. Oncol Rep. 2018 Mar,39(3):1299-1305. doi: 10.3892/or.2018.6184.
- (2018) Wang X., Zhang M., Ping F., et al. Identification and therapeutic intervention of coactivated anaplastic lymphoma kinase, fibroblast growth factor receptor 2, and ephrin type-A receptor 5 kinases in hepatocellular carcinoma. Hepatology. 2018 Jan 21. doi: 10.1002/hep.29792.
- Kato K. et al. (2016) The anti-diabetic drug metformin inhibits pancreatic cancer cell proliferation in vitro and in vivo: Study of the microRNAs associated with the antitumor effect of metformin. Oncology Reports 35(3):1582-92. doi: 10.3892/or.2015.4496
- Catalog Number
AAH-PER-1-4-RB - Supplier
RayBiotech - Size
- Shipping
Blue Ice
Price
611,00 €
