Human Platelet Derived Growth Factor-AA (PDGF-AA)
| Specifications | |
|---|---|
| Molecular Weight: | 14.4/28.9 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 50 ng/mL |
| Activity Assay: | NR6R-3T3 cell proliferation |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA) |
| Additional Information | |
|---|---|
| Synonyms: | GDGF, ODGF |
| Organism: | Human |
| Accn. No.: | P04085 |
Sequence Information
MSIEEAVPAV CKTRTVIYEI PRSQVDPTSA NFLIWPPCVE VKRCTGCCNT SSVKCQPSRV HHRSVKVAKV EYVRKKPKLK EVQVRLEEHL ECACATTSLN PDYREEDTGR PRESGKKRKR KRLKPT
Background
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-a, TGF-b and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-a and PDGFR-b.
- Catalog Number
100-16-10UG-SHE - Supplier
Fujifilm Irvine Scientific - Size
- Shipping
RT
Price
225,00 €
