Pamiparib maleate
| Specifications | |
|---|---|
| CAS Number: | 2086689-94-1 |
| Synonyms: | BGB-29 maleat 0 |
| Formula: | C44H42F2N8O14 |
| Molecular Weight: | 944,859 |
Description
Pamiparib is a highly potent and selective PARP inhibitor. BGB-290 selectively binds to PARP and prevents PARP-mediated repair of single-strand DNA breaks via the base-excision repair (BER) pathway. This enhances the accumulation of DNA strand breaks, promotes genomic instability, and eventually leads to apoptosis.
Price
2.273,00 €
