Trilencer-27 siRNA Sets
siRNA Trilencer-27 sets are dicer-substrate duplexes that provide two critical improvements over the use of traditional 21mer siRNA designs. 27mer siRNA takes advantage of the natural processing by dicer producing 10-fold higher potency and specificity than shorter 21mer RNAi forms.
27mer dicer-substrate duplexes also evade the radar of the mammalian interferon response when expressed in mammalian cells and initiates strong and specific gene silencing.
Features & Benefits
- Genome-wide coverage against human, mouse and rat
- 27mer dicer-substrate duplex for higher potency and minimal interferon response
- Guaranteed gene knockdown (>=70%)
- 3 gene-specific siRNAs, 1 negative control included
Download the siRNA-27 Application Guide