RSL3
| Specifications | |
|---|---|
| CAS Number: | 1219810-16-8 |
| Synonyms: | 1S,3R-RSL3 |
| Formula: | C23H21ClN2O5 |
| Molecular Weight: | 440,88 |
Description
RSL3 (RSL3 1S) is an inhibitor of GPX4, and inhibits system xc- that blocks GSH synthesis (IC50=100 nM). RSL3 is a VDAC-independent activator of ferroptosis that is selective for tumor cells carrying oncogenic RAS.
