Recombinant Mouse IL6 protein(His tag)
Specifications | |
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Molecular Weight: | 23 kDa |
Tag: | C-His |
Source: | HEK293 Cells |
Purity: | > 95% as determined by reducing SDS-PAGE. |
Endotoxin Level: | < 1.0 EU/mg of the protein as determined by the LAL method. |
Format: | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Additional Information | |
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Synonyms: | BSF;Interleukin;Interleukin HP;IFNB;B-cell hybridoma growth factor;BSF2;CDF;HGF;HSF;IFNB2;IL 6;Interleukin HP-1;Interleukin-6;Il-6;Il6 |
Organism: | Mouse |
Accn. No.: | P08505 |
Sequence Information
Met1-Thr211
Background
Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism (Probable). Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway.The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
- Catalog Number
PDMM100194-500ug-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
1.454,00 €