Recombinant Mouse IL6 protein(His tag)

Specifications
Molecular Weight:23 kDa
Tag:C-His
Source:HEK293 Cells
Purity:> 95% as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU/mg of the protein as determined by the LAL method.
Format:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Additional Information
Synonyms:BSF;Interleukin;Interleukin HP;IFNB;B-cell hybridoma growth factor;BSF2;CDF;HGF;HSF;IFNB2;IL 6;Interleukin HP-1;Interleukin-6;Il-6;Il6
Organism:Mouse
Accn. No.:P08505

Sequence Information

Met1-Thr211

Background

Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism (Probable). Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway.The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.
Price
1.454,00 €
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