Recombinant Human IL-28B/IFN-lambda-3 protein (His tag)
| Specifications | |
|---|---|
| Molecular Weight: | 19.1 kDa |
| Tag: | N-His |
| Source: | E.coli |
| Purity: | > 95% as determined by reducing SDS-PAGE. |
| Endotoxin Level: | < 10 EU/mg of the protein as determined by the LAL method. |
| Format: | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
| Additional Information | |
|---|---|
| Synonyms: | Cytokine Zcyto;ZCYTO;IFNL3;IFN-lambda-3;IFN-lambda-4;IL-28B;IL-28C;IL28B;IL28C;Cytokine Zcyto22;IFNL4;IFN-lambda 3;interferon lambda 3;Interferon Lambda-3;Interferon Lambda-4;Interleukin-28B;Interleukin-28C;ZCYTO22 |
| Organism: | Human |
| Accn. No.: | Q8IZI9 |
Sequence Information
Val 22-Val 196
Background
Interleukin-28B, also known as Cytokine Zcyto22, Interferon lambda-3, Interferon lambda-4, IFNL3, IFNL4, ZCYTO22 and IL28B, is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition, IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.
- Catalog Number
PDEH100915-100ug-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
Price
518,00 €
