Human Vascular Endothelial Growth Factor-121 (VEGF-121)
| Specifications | |
|---|---|
| Molecular Weight: | 14.2/28.4 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 5 ng/mL |
| Activity Assay: | HUVEC proliferation |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA) |
| Additional Information | |
|---|---|
| Synonyms: | VEGF-A, VPF, glioma-derived endothelial cell mitogen |
| Organism: | Human |
| Accn. No.: | P15692-9 |
Sequence Information
MAPMAEGGGQ NHHEVVKFMD VYQRSYCHPI ETLVDIFQEY PDEIEYIFKP SCVPLMRCGG CCNDEGLECV PTEESNITMQ IMRIKPHQGQ HIGEMSFLQH NKCECRPKKD RARQEKCDKP RR
Background
Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with one being VEGF-121. The VEGF-121 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell function.
- Catalog Number
100-116AF-1MG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
5.573,00 €
