Human Pleiotrophin (Pleiotrophin)
| Specifications | |
|---|---|
| Molecular Weight: | 15,4 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | Currently undetermined |
| Activity Assay: | Currently undetermined |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, pH 7.5 |
| Additional Information | |
|---|---|
| Synonyms: | HBBM, HBGF-8, NEGF1, HARP |
| Organism: | Human |
| Accn. No.: | P21246 |
Sequence Information
MGKKEKPEKK VKKSDCGEWQ WSVCVPTSGD CGLGTREGTR TGAECKQTMK TQRCKIPCNW KKQFGAECKY QFQAWGECDL NTALKTRTGS LKRALHNAEC QKTVTISKPC GKLTKPKPQA ESKKKKKEGK KQEKMLD
Background
Pleiotrophin (PTN) is a heparin-binding growth factor that has mitogenic effects on fibroblast, epithelial, and endothelial cells. PTN is made by many tissues, but is predominantly secreted by nervous tissue during development. PTN induces neurite outgrowth and is involved in tumor growth and metastasis. PTN binds with low affinity to the cell surface receptor nucleolin to inhibit HIV-1 infection. PNT can also binds the receptor protein tyrosine phosphatase type Z (PTPRZ), syndecan-3, and anaplastic lymphoma kinase (ALK) receptors.
- Catalog Number
100-55-5UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
95,00 €
