Human Oncostatin-M (Oncostatin M)
| Specifications | |
|---|---|
| Molecular Weight: | 23,8 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 4 ng/mL |
| Activity Assay: | TF-1 cell proliferation |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, pH 7.5 |
| Additional Information | |
|---|---|
| Synonyms: | Onc-M |
| Organism: | Human |
| Accn. No.: | P13725 |
Sequence Information
MAAIGSCSKE YRVLLGQLQK QTDLMQDTSR LLDPYIRIQG LDVPKLREHC RERPGAFPSE ETLRGLGRRG FLQTLNATLGCVLHRLADLE QRLPKAQDLE RSGLNIEDLE KLQMARPNIL GLRNNIYCMA QLLDNSDTAE PTKAGRGASQ PPTPTPASDA FQRKLEGCRFLHGYHRFMHS VGRVFSKWGE SPNRSRRHSP HQALRKGVRR
Background
Oncostatin M (OSM) is a cytokine that is produced by macrophages, dendritic cells, and T lymphocytes during inflammatory events. The Type-I and Type-II OSM receptors are located on the cell surface of endothelial and tumor cells, contain the glycoprotein 130 (gp130) subunit, and activate the JAK/STAT signaling pathway. OSM functions to inhibit tumor cell proliferation, induce liver stem cell maturation, regulate cytokine production during hematopoiesis and inflammation, stimulate bone formation, and promote nervous system development.
- Catalog Number
100-56-500UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
4.055,00 €
