Human Nerve GRO betath Factor beta (NGF-beta)
| Specifications | |
|---|---|
| Molecular Weight: | 13,6 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 5 ng/mL |
| Activity Assay: | TF-1 cell proliferation |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA) |
| Additional Information | |
|---|---|
| Synonyms: | beta-NGF |
| Organism: | Human |
| Accn. No.: | P01138 |
Sequence Information
MSSSHPIFHR GEFSVCDSVS VWVGDKTTAT DIKGKEVMVL GEVNINNSVF KQYFFETKCR DPNPVDSGCR GIDSKHWNSY CTTTHTFVKA LTMDGKQAAW RFIRIDTACV CVLSRKAVRR A
Background
Nerve growth factor beta (beta-NGF) is a neurotrophic factor that is important for the development and maintenance of sensory and sympathetic neurons. beta-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. beta-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat beta-NGF proteins are cross-reactive.
- Catalog Number
100-38-20UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
225,00 €
