Human Macrophage Inflammatory Protein-4 (MIP-4 / CCL18)
| Specifications | |
|---|---|
| Molecular Weight: | 7,9 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | Currenlty undetermined |
| Activity Assay: | Bioactive protein, but not acceptance criteria established |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA) |
| Additional Information | |
|---|---|
| Synonyms: | CCL18, PARC, AMAC-1, DC-CK1 |
| Organism: | Human |
| Accn. No.: | P55774 |
Sequence Information
AQVGTNKELC CLVYTSWQIP QKFIVDYSET SPQCPKPGVI LLTKRGRQIC ADPNKKWVQK YISDLKLNA
Background
Macrophage inflammatory protein-4 (MIP-4), also called CCL18, is a chemokine expressed in the lymph nodes, lungs, placenta, and bone marrow. MIP-4 receptors include the chemokine receptor 8 (CCR8), the G protein-coupled receptor 30 (GPR30), and the phosphatidylinositol transfer protein membrane-associate 3 (PITPNM3). MIP-4 acts as a chemoattractant for naive T cells, CD4+ T cells, CD8+ T cells, and nonactivated lymphocytes. Further, MIP-4 promotes breast cancer metastasis and attenuates the activation of acute lymphocytic leukemia B cells.
- Catalog Number
100-136-10UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
225,00 €
