Human Interleukin-7 (IL-7)
| Specifications | |
|---|---|
| Molecular Weight: | 17,5 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥97% |
| Activity: | 1 ng/mL |
| Activity Assay: | 2E8 cell proliferation |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 10 mM acetic acid, pH 7.5 |
| Additional Information | |
|---|---|
| Synonyms: | Lymphopoietin 1 (LP-1), pre-B cell Factor |
| Organism: | Human |
| Accn. No.: | P13232 |
Sequence Information
MDCDIEGKDG KQYESVLMVS IDQLLDSMKE IGSNCLNNEF NFFKRHICDA NKEGMFLFRA ARKLRQFLKM NSTGDFDLHL LKVSEGTTIL LNCTGQVKGR KPAALGEAQP TKSLEENKSL KEQKKLNDLC FLKRLLQEIK TCWNKILMGT KEH
Background
Interleukin 7 (IL-7) is a hematopoietic cytokine that is an important regulator of B and T cell development. IL-7 is secreted by bone marrow and thymic stromal cells, dendritic cells, intestinal epithelial cells, hepatocytes, and keratinocytes. IL-7 signals through the interleukin 7 receptor (IL-7R) to promote the differentiation of hematopoietic stem cells into T cells, B cells, and natural killer cells. IL-7 is also a regulator of intestinal mucosal lymphocyte proliferation. Human and mouse IL-7 show species cross-reactivity.
Price
225,00 €
