Human Interferon-alpha 2b (IFN alpha 2b)

Specifications
Molecular Weight:19,4
Tag:None
Source:E.coli
Purity:≥95%
Activity:0.005
Activity Assay:Viral CPE assay using EMC virus on A549 cells
Format:Lyophilized from a 0.2 µm filtered solution containing 0.1% Trifluoroacetic Acid (TFA)
Additional Information
Synonyms:Type I Interferon, Alpha 2
Organism:Human
Accn. No.:P01563

Sequence Information

MCDLPQTHSL GSRRTLMLLA QMRRISLFSC LKDRHDFGFP QEEFGNQFQK AETIPVLHEM IQQIFNLFST KDSSAAWDET LLDKFYTELY QQLNDLEACV IQGVGVTETP LMKEDSILAV RKYFQRITLY LKEKKYSPCA WEVVRAEIMR SFSLSTNLQE SLRSKE

Background

Interferon-alpha 2b (IFN-α2b) is a type I interferon made by leukocytes during viral infection. The JAK-STAT pathway mediates the antiviral and anti-cell proliferation activities of IFN-α2b. IFN-α proteins are widely used as standard treatments during antiviral and antineoplastic therapies. The IFN-α2b variant differs from IFN-α2a by one amino acid.
Price
1.274,00 €
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