Human Fibroblast Growth Factor acidic (FGF-acidic)
| Specifications | |
|---|---|
| Molecular Weight: | 16 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 2 ng/mL |
| Activity Assay: | NR6R-3T3 cell proliferation |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, 150 mM Sodium Sulfate, pH 7.5 |
| Additional Information | |
|---|---|
| Synonyms: | FGF1, HBGF-1, Beta-endothelial growth factor, ECGF-beta |
| Organism: | Human |
| Accn. No.: | P05230 |
Sequence Information
MFNLPPGNYK KPKLLYCSNG GHFLRILPDG TVDGTRDRSD QHIQLQLSAE SVGEVYIKST ETGQYLAMDT DGLLYGSQTP NEECLFLERL EENHYNTYIS KKHAEKNWFV GLKKNGSCKR GPRTHYGQKA ILFLPLPVSS D
Background
Acidic fibroblast growth factor (aFGF), also known as FGF1, is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. aFGF regulates cardiogenesis through protein kinase C signaling. aFGF also functions as an insulin sensitizer and mediates adipose tissue remodeling. High serum levels of aFGF are associated with type 2 diabetes mellitus (T2DM), suggesting a pathogenic role of aFGF during T2DM.
- Catalog Number
100-29-50UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
225,00 €
