Human Fibroblast Growth Factor-21 (FGF-21)
| Specifications | |
|---|---|
| Molecular Weight: | 19,5 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 500 ng/mL |
| Activity Assay: | NIH-3T3 proliferation with β-klotho and heparin |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, 100 mM Sodium Chloride, pH 7.5 |
| Additional Information | |
|---|---|
| Synonyms: | FGFL |
| Organism: | Human |
| Accn. No.: | Q9NSA1 |
Sequence Information
MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
Background
Fibroblast growth factor 21 (FGF21) is an endocrine hormone that regulates energy homeostasis and exerts cardioprotective functions during heart injury. FGF21 is expressed in the liver, pancreas, heart, and adipose tissues. FGF21 signaling is activated through the FGFR1c receptor and β-Klotho co-receptor. FGF21 is an important regulator of glucose uptake and reduces cell apoptosis under stress conditions.
- Catalog Number
100-148AF-100UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
598,00 €
