Human CD40 Ligand (CD40-Ligand)
| Specifications | |
|---|---|
| Molecular Weight: | 16,3 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 50 ng/mL |
| Activity Assay: | Activity of HEK-blue™ CD40L cells |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, pH 7.5 |
| Additional Information | |
|---|---|
| Synonyms: | TNFSF5, TRAP, CD154, gp39, T-BAM |
| Organism: | Human |
| Accn. No.: | P29965 |
Sequence Information
MQKGDQNPQI AAHVISEASS KTTSVLQWAE KGYYTMSNNL VTLENGKQLT VKRQGLYYIY AQVTFCSNRE ASSQAPFIAS LWLKSPGRFE RILLRAANTH SSAKPCGQQS IHLGGVFELQ PGASVFVNVT DPSQVSHGTG FTSFGLLKL
Background
CD40 Ligand (CD40L), or CD154, is a membrane glycoprotein and differentiation antigen that is expressed on the surface of T cells, monocytes, basophils, eosinophils, platelets, dendritic cells, and endothelial cells. CD40L binds and activates the CD40 receptor on antigen-presenting cells. CD40L stimulates B cell proliferation, immunoglobulin class switching, and antibody secretion. CD40L also induces cytokine production and tumoricidal activity in peripheral blood monocytes. CD40L is a co-stimulator of activated T cell proliferation and inflammatory protein production.
- Catalog Number
100-25-500UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
979,00 €
