Human 4-1BB Ligand / TNFSF9 (71-254) Protein, Fc Tag, active trimer, premium grade
| Specifications | |
|---|---|
| Category: | Immune Checkpoint Proteins |
| Molecular Weight: | 87.5 kDa |
| Tag: | N-Fc |
| Label / Conjugate: | Unconjugated |
| Purity: | 95% |
| Endotoxin Level: | 0.01 EU per μg |
| Format: | Powder |
| Host: | HEK293 |
| Additional Information | |
|---|---|
| Synonyms: | 4-1BB Ligand,TNFSF9,CD137L |
| Organism: | Human |
| Accn. No.: | P41273-1 |
Sequence Information
Arg 71 - Glu 254
Background
Tumor necrosis factor ligand superfamily member 9 (4-1BBL) is also known as 4-1BB ligand, CD137L or TNFSF9, which is a cytokine that binds to TNFRSF9. 4-1BBL is the high affinity ligand of 4-1BB. 4-1BBL induces the proliferation of activated peripheral blood T-cells. Also, 4-1BBL may have a role in activation-induced cell death (AICD). Furthermore, 4-1BBL may play a role in cognate interactions between T-cells and B-cells/macrophages. As for diseases, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Price
642,00 €
