Hamster (CHO) Nidogen-1 (NDN) ELISA

Nidogen-1 is a CHO host cell protein (HCP) found in abundance in both batch and fed-batch cultures. It is difficult to remove and negatively affects products quality (1,2).

1. Park, J.H. et al. (2017). Proteomic Analysis of Host Cell Protein Dynamics in the Culture Supernatants of Antibody-Producing CHO Cells. Nature: Scientific Reports. 7:44246. DOI: 10.1038/srep44246.

2. Kol, S. et al. (2020). Multiplex secretome engineering enhances recombinant protein production and purity. Nature Communications. 11:1908