Animal-Free Equine PDGF-BB
| Specifications | |
|---|---|
| Molecular Weight: | 24,8 |
| Tag: | None |
| Source: | E.coli |
| Purity: | ≥95% |
| Activity: | 30 ng/mL |
| Activity Assay: | NR6R 3T3 proliferation |
| Format: | Lyophilized from a 0.2 µm filtered solution containing 10 mM Sodium Phosphate, pH 7.5 |
| Additional Information | |
|---|---|
| Synonyms: | GDGF, ODGF |
| Organism: | Equine |
| Accn. No.: | XP_005606703 |
Sequence Information
MSLGSLAVAE PAMIAECKTR TEVFEISRRL IDRTNANFLV WPPCVEVQRC SGCCNNRHVQ CRPTQVQLRP VQVRKIEIVR KKPTFKKATV TLEDHLACKC ETVGAARPVT
Background
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β, and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells. PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.
- Catalog Number
400-17AF-5UG-SHE - Supplier
Fujifilm Biosciences - Size
- Shipping
RT
Price
106,00 €
