Afatinib oxalate
| Specifications | |
|---|---|
| CAS Number: | 1398312-64-5 |
| Formula: | C28H29ClFN5O11 |
| Molecular Weight: | 666,01 |
Description
Afatinib (BIBW 2992) oxalate is an irreversible, orally active bispecific inhibitor of the ErbB family (EGFR and HER2) that acts on EGFRwt (IC50: 0.5 nM), EGFRL858R (IC50: 0.4 nM), EGFRL858R/T790M ( IC50: 10 nM) and HER2 (IC50: 14 nM). Afatinib oxalate can be used to study esophageal squamous cell carcinoma (ESCC), non-small cell lung cancer (NSCLC) and gastric cancer.
Price
2.143,00 €
