Recombinant Mouse S100A15/S100A7A Protein
| Specifications | |
|---|---|
| Molecular Weight: | 12.9 kDa |
| Tag: | None |
| Source: | E.coli |
| Purity: | >95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | <1.0 EU per µg of the protein as determined by the LAL method. |
| Activity: | Testing in progress |
| Format: | Lyophilized from sterile PBS, pH 7.4. |
| Additional Information | |
|---|---|
| Synonyms: | S100 calcium-binding protein A15A; Protein S100-A15A; Protein S100-A7A; S100 calcium-binding protein A7A; S100a15a |
| Organism: | Mouse |
| Accn. No.: | Q6S5I3 |
Sequence Information
Met1-Tyr108
Background
Members of the S100 protein family are involved in calcium- or zinc-dependent cellular functions and regulate immune-mechanisms, cell proliferation and differentiation. Some S100 members have been established as tumor markers because they are dysregulated during carcinogenesis. Psoriasin (S100A7) and koebnerisin (S100A15) are highly homologous proteins that have been first described in psoriasis, which is characterized by disturbed epidermal maturation and chronic inflammation. Several studies showed that the coexpression of the hS100A7 and hS100A15 in psoriasis suggests that both proteins participate in keratinocyte maturation, proliferation and/or skin inflammation.
Price
112,00 €
