Recombinant Human CCL14 Protein
| Specifications | |
|---|---|
| Molecular Weight: | 8.7 kDa |
| Tag: | N-His |
| Source: | E.coli |
| Purity: | >95 % as determined by reducing SDS-PAGE. |
| Endotoxin Level: | Please contact us for more information. |
| Activity: | Testing in progress |
| Format: | Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80. |
| Additional Information | |
|---|---|
| Synonyms: | C-C motif chemokine 14,CC-1,CC-3,HCC-1,HCC-1(1-74),HCC-3,NCC-2,Small-inducible cytokine A14,NCC2,SCYA14 |
| Organism: | Human |
| Accn. No.: | Q16627 |
Sequence Information
Thr20-Asn93
Background
Has weak activities on human monocytes and acts via receptors that also recognize MIP-1 alpha. It induces intracellular Ca2+ changes and enzyme release, but no chemotaxis, at concentrations of 100-1,000 nM, and is inactive on T-lymphocytes, neutrophils, and eosinophil leukocytes. Enhances the proliferation of CD34 myeloid progenitor cells. The processed form HCC-1(9-74) is a chemotactic factor that attracts monocytes, eosinophils, and T-cells and is a ligand for CCR1, CCR3 and CCR5.
Price
112,00 €
