PE Anti-Human CD95/Fas Antibody[HFE7A/APO]

Specifications
Type:Primary Antibody
Clonality:Recombinant
Clone Name:HFE7A/APO
Host:Mouse
Reactivity:Human
Isotype:Mouse IgG2a, κ
Label:PE
Concentration:5 μL/Test
Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Additional Information
Synonyms:APT1;FAS1;TNFRSF6;Apo-1 antigen;FASLG receptor
Gene Symbol:FAS
Organism:Homo sapiens
Gene ID:355
UniProt ID:P25445

Applications

FCM

Background

CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.
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Dr. Kristin Kördel

Tel. +49 (0) 6221 71415 16

info@biocat.com

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