FITC Anti-Human CD22 Antibody[HIB22]
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | HIB22 |
| Host: | Mouse |
| Reactivity: | Human |
| Isotype: | Mouse IgG1, κ |
| Label: | FITC |
| Concentration: | 5 uL/Test |
| Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Applications
FCM
Background
CD22 is a 130 kD type I transmembrane glycoprotein also known as Siglec-2 and BL-CAM. It is a member of the immunoglobulin superfamily (sialoadhesion subgroup). CD22 is expressed in the cytoplasm of pro-B and pre-B cells, and on the surface of mature B and activated B cells, but not on plasma cells. CD22 is present in the B cell receptor complex and associates with SHP-1, Syk, Lck, Lyn, and phospholipase Cγ1. A primary function of CD22 is thought to be in limiting antigen receptor signaling by modulating B cell activation threshold. CD22 has been shown to bind to CD45RO and CD75, although the natural ligands for this molecule remain controversial.
- Catalog Number
E-AB-F1321C-100Testsx2-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
- Price
- Please inquire
