PE Anti-Human CD11a Antibody[HI111]

Specifications
Clonality:Monoclonal
Clone Name:HI111
Host:Mouse
Reactivity:Human
Isotype:Mouse IgG1, κ
Label:PE
Concentration:5 μL/Test
Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Additional Information
Synonyms:Integrin alpha-L;Itgal;CD11 antigen-like family member A;LFA-1A;Lymphocyte antigen 15;Ly-15;CD11a
Gene Symbol:ITGAL
Organism:Homo sapiens
Gene ID:3683
UniProt ID:P20701
Control Antibody:E-AB-F09792D

Applications

FCM

Background

CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).
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Please contact:

Dr. Kristin Kördel

Tel. +49 (0) 6221 71415 16

info@biocat.com

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