PerCP/Cyanine5.5 Anti-Human CD11b Antibody[ICRF44]

Specifications
Type:Primary Antibody
Clonality:Monoclonal
Clone Name:ICRF44
Host:Mouse
Reactivity:Human
Isotype:Mouse IgG1, κ
Label:PerCP/Cyanine5.5
Concentration:5 uL/Test
Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Additional Information
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Gene Symbol:ITGAM
Organism:Homo sapiens
Gene ID:3684
UniProt ID:P11215
Control Antibody:E-AB-F09792J

Applications

FCM

Background

CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.
  • Catalog Number
    E-AB-F1146J-100Testsx2-ELS
  • Supplier
    Elabscience
  • Size
  • Shipping
    Blue Ice
  • Price
  • Please inquire
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you need any help?

Please contact:

Dr. Kristin Kördel

Tel. +49 (0) 6221 71415 16

info@biocat.com

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