FITC Anti-Human CD45RO Antibody[UCHL1]
| Specifications | |
|---|---|
| Type: | Primary Antibody |
| Clonality: | Monoclonal |
| Clone Name: | UCHL1 |
| Host: | Mouse |
| Reactivity: | Human |
| Isotype: | Mouse IgG2a, κ |
| Label: | FITC |
| Concentration: | 5 uL/Test |
| Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
| Additional Information | |
|---|---|
| Gene Symbol: | PTPRC |
| Organism: | Homo sapiens |
| Gene ID: | 5788 |
| Control Antibody: | E-AB-F09802C |
Applications
FCM
Background
CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.
- Catalog Number
E-AB-F1139C-100Testsx2-ELS - Supplier
Elabscience - Size
- Shipping
Blue Ice
- Price
- Please inquire
