Elab Fluor® 647 Anti-Human CD32 Antibody[IV-3]

Specifications
Type:Primary Antibody
Clonality:Monoclonal
Clone Name:IV-3
Host:Mouse
Reactivity:Human
Isotype:Mouse IgG2b, κ
Label:Elab Fluor® 647
Concentration:5 uL/Test
Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Additional Information
Synonyms:Low affinity immunoglobulin gamma Fc region receptor II-b;FCGR2B;IgG Fc receptor II-b;CDw32;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;CD32;FCG2; IGFR2;
Gene Symbol:FCGR2A
Organism:Homo sapiens
Gene ID:2212
UniProt ID:P31994
Control Antibody:E-AB-F09812M

Applications

FCM

Background

CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).
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Dr. Kristin Kördel

Tel. +49 (0) 6221 71415 16

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