DriverMap Mouse Targeted Expression Profiling Kit (PanCancer/LINCSx/Hallmark Panel) (96 multiplex) Add to Cart
Combine the sensitivity of qRT-PCR and the throughput of NGS
Cellecta’s DriverMap Assay for murine genes measures expression levels for 4,700 targets. This first DriverMap Mouse Panel was designed to target the murine orthologs of the human genes targeted in three of Cellecta’s DriverMap Human Predesigned Expression Profiling Panels—the Hallmarks Signatures, LINCS 1000x, and Pan-Cancer Pathway Panels. The activity of this set of genes provides a basis to evaluate the biology associated with disease progression and drug response in most in vivo or in vitro murine models.
• Easy and highly specific expression analysis of 4,700 key mouse genes
• Simple profiling of key drug- and cancer-related gene targets
• Single-tube, multiplex protocol with simple analysis for rapid results
• Robust, reproducible data from low-input RNA samples—start with as little as 10 pg total RNA
• Rapid results with DriverMap Deconvolution Software that provides you with gene-specific expression data in an Excel spreadsheet format directly from Illumina Fastq raw reads.
All the benefits of the DriverMap Technology
The DriverMap Mouse Targeted Profiling Panel utilizes the same single-tube multiplex assay approach as the DriverMap Human Genome-Wide Expression Profiling Assay, which provides robust, quantitative, and reproducible measurements of each expressed gene over as much as 5-orders of magnitude. The DriverMap approach overcomes the low sensitivity and specificity challenges of current RNA sequencing technologies. It greatly simplifies the protocols for data generation and analysis while providing robust specificity, sensitivity and reproducibility of differentially expressed, protein-coding genes.
DriverMap kits include all necessary reagents and components required to generate 96 targeted RNA-Seq libraries ready for sequencing. The DriverMap technology can effectively be used with total RNA derived from blood, cell culture, or fresh frozen or formalin-fixed paraffin-embedded (FFPE) tissue.
For rapid analysis, each kit also comes with the DriverMap Analysis Software that enables visualization of gene-specific expression data in an Excel spreadsheet format directly from Illumina NGS FASTQ raw reads.
Tarca AL et al. (2019) Targeted expression profiling by RNA-Seq improves detection of cellular dynamics during pregnancy and identifies a role for T cells in term parturition.
Scientific Reports 9:848.