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Cancer Cells

Liquid Biopsy - Biomarker Discovery in Blood and Urine

  • Blood & Urine Collection and Preservation
  • Circulating cell-free DNA Isolation
  • Circulating cell-free RNA Isolation
  • Exosome Isolation
  • Exosomal DNA and RNA Isolation
  • NGS DNA Library Preparation

Liquid biopsy is a method to obtain biomarkers directly from body fluids such as blood or urine instead of solid tissue. It is a simple and non-invasive alternative to surgical biopsies. With the growing recognition that circulating cell-free DNA (cfDNA) can provide critical information on diseases that are normally difficult to detect with standard approaches - including cancer - the interest in liquid biopsy methods for biomarker discovery and disease research is on the rise. In addition to cfDNA, exosomes are also a rich source of biomarkers that are amenable to the straightforward liquid biopsy approach.

To facilitate biomarker discovery in liquid biopsies, BioCat offers comprehensive tools for the complete workflow from the collection and preservation of blood or urine through the enrichment, purification and NGS analysis of cfDNA, cfRNA and exosomal DNA or RNA.



Blood & Urine Collection and Preservation

Blood cf-DNA/cf-RNA Preservative Tubes 63950-NB 50 tubes   497 € DETAILS
Blood cf-DNA/cf-RNA Preservative Tubes - CE-marked (for IVD) Dx63950-NB 50 tubes   516 € DETAILS
Blood cf-DNA/cf-RNA Preservative Tubes 63960-NB 100 tubes   933 € DETAILS
Urine Collection and Preservation Tube 5 cc (1 ml to 5 ml input) 18118-NB 50 tubes   612 € DETAILS
Urine Collection and Preservation Tubes 50 cc (5 ml to 45 ml input) 18113-NB 50 tubes   957 € DETAILS
Urine Collection and Preservation Tube 15 cc (5 ml to 15 ml input) 18122-NB 50 tubes   778 € DETAILS
Urine Preservative, Liquid Format (Single Dose Ampules) 18126-NB 50 ampules   551 € DETAILS


Circulating cell-free DNA and RNA Isolation

Plasma/Serum circulating cell-free DNA and RNA Isolation

Convenient spin column format if not mentioned otherwise.

Plasma/Serum Cell-Free Circulating DNA (cfc DNA, ccf DNA) Purification Mini Kit 55100-NB 50 preps   246 € DETAILS
Plasma/Serum Cell-Free Circulating DNA Purification Mini Kit - CE-marked (for IVD) Dx55100-NB 50 preps   273 € DETAILS
Plasma/Serum Cell-Free Circulating DNA (cfc DNA, ccf DNA) Purification Micro Kit 55500-NB 50 preps   246 € DETAILS
Plasma/Serum Cell-Free Circulating DNA Purification Micro Kit - CE-marked (for IVD) Dx55500-NB 50 preps   273 € DETAILS
Plasma/Serum Cell-Free Circulating DNA (cfc DNA, ccf DNA) Purification Midi Kit 55600-NB 20 preps   437 € DETAILS
Plasma/Serum Cell-Free Circulating DNA Purification Midi Kit - CE-marked (for IVD) Dx55600-NB 20 preps   471 € DETAILS
Plasma/Serum Cell-Free Circulating DNA (cfc DNA, ccf DNA) Purification Maxi Kit 55800-NB 10 preps   332 € DETAILS
Plasma/Serum Cell-Free Circulating DNA Purification Maxi Kit - CE-marked (for IVD) Dx55800-NB 10 preps   362 € DETAILS
Plasma/Serum Circulating DNA Isolation Mini Kit slurry format - for Research Use 50600-NB 50 preps   223 € DETAILS
Plasma/Serum Circulating DNA Isolation Mini Kit slurry format - CE-marked (for IVD) Dx50600-NB 50 preps   230 € DETAILS
Plasma/Serum Circulating DNA Isolation Midi Kit slurry format 51200-NB 20 preps   261 € DETAILS
Plasma/Serum Circulating DNA Isolation Maxi Kit slurry format 51300-NB 10 preps   261 € DETAILS
Plasma/Serum Cell-Free Circulating and Viral Nucleic Acid Purification Mini Kit 56300-NB 50 preps   356 € DETAILS
Plasma/Serum Cell-Free Circulating and Viral Nucleic Acid Purification Midi Kit 56400-NB 20 preps   393 € DETAILS
Plasma/Serum Cell-Free Circulating and Viral Nucleic Acid Purification Maxi Kit 56500-NB 10 preps   294 € DETAILS
cfPure Cell Free DNA Extraction Kit (magnetic bead-based, automatization-friendly) for isolating cfDNA from 100 ml human plasma/serum (100 x 1 ml or 10 x 10 ml, scalable) K5011610-BC 1 kit   511 € DETAILS
cfPure Cell Free DNA Extraction Kit (magnetic bead-based, automatization-friendly) for isolating cfDNA from 250 ml human plasma/serum (250 x 1 ml or 25 x 10 ml, scalable) K5011625-BC 1 kit   720 € DETAILS
EpiQuik Circulating Cell-Free DNA (cf DNA, cfc DNA) Isolation Easy Kit (magnetic-bead based) for isolating cfDNA from 0.5 ml Plasma/Serum P-1065-25-EP 25 preps   219 € DETAILS
EpiQuik Circulating Cell-Free DNA (cf DNA, cfc DNA) Isolation Easy Kit (magnetic-bead based) for isolating cfDNA from 0.5 ml Plasma/Serum P-1065-50-EP 50 preps   305 € DETAILS


Urine circulating cell-free DNA and RNA Isolation

Convenient spin column format if not mentioned otherwise.

Urine Cell-Free Circulating DNA Purification Mini Kit 56600-NB 50 preps   276 € DETAILS
Urine Cell-Free Circulating DNA Purification Midi Kit 56700-NB 20 preps   437 € DETAILS
Urine Cell-Free Circulating DNA Purification Maxi Kit 56800-NB 10 preps   332 € DETAILS
Urine Cell-Free Circulating RNA Purification Mini Kit 56900-NB 50 preps   431 € DETAILS
Urine Cell-Free Circulating RNA Purification Midi Kit 57000-NB 20 preps   427 € DETAILS
Urine Cell-Free Circulating RNA Purification Maxi Kit 57100-NB 10 preps   340 € DETAILS
Urine Cell-Free Circulating and Viral Nucleic Acid Purification Mini Kit 59900-NB 50 preps   340 € DETAILS
Urine Cell-Free Circulating and Viral Nucleic Acid Purification Midi Kit 60000-NB 20 preps   402 € DETAILS
Urine Cell-Free Circulating and Viral Nucleic Acid Purification Maxi Kit 60100-NB 10 preps   298 € DETAILS


Exosome & Nucleic Acids Isolation

Exosome Isolation

ExoQuick Exosome Precipitation Solution for Serum, Plasma and Tumor Ascites Fluid (5 ml) EXOQ5A-1-SBI 75 rxns (250 ul sample volume)   436 € DETAILS
ExoQuick Exosome Precipitation Solution for Serum, Plasma and Tumor Ascites Fluid (20 ml) EXOQ20A-1-SBI 300 rxns (250 ul sample volume)   1155 € DETAILS
ExoQuick PLUS Exosome Purification Kit -Serum and Plasma (10 reactions) for efficient reduction of abundant proteins and better detection of low-abundance biomarkers. EQPL10A-1-SBI 10 rxns   568 € DETAILS
ExoQuick-TC Exosome Precipitation Solution for Culture Media, Spinal Fluid and Urine (10 ml) EXOTC10A-1-SBI 10 rxns (5 ml sample volume)   404 € DETAILS
ExoQuick-TC Exosome Precipitation Solution for Culture Media, Spinal Fluid and Urine (50 ml) EXOTC50A-1-SBI 50 rxns (5 ml sample volume)   1161 € DETAILS
Plasma/Serum Exosome Purification Mini Kit 57400-NB 50 preps   878 € DETAILS
Plasma/Serum Exosome Purification Midi Kit 57500-NB 25 preps   888 € DETAILS
Plasma/Serum Exosome Purification Maxi Kit 57600-NB 15 preps   722 € DETAILS
Urine Exosome Purification Mini Kit 57700-NB 50 preps   1162 € DETAILS
Urine Exosome Purification Midi Kit 57800-NB 25 preps   888 € DETAILS
Urine Exosome Purification Maxi Kit 57900-NB 15 preps   722 € DETAILS


Exosome, Exosomal DNA and circulating cell-free DNA Isolation

XCF COMPLETE Exosome and cfDNA Isolation Kit (for Serum and Plasma) XCF100A-1-SBI 20 reactions   632 € DETAILS
XCF Exosomal DNA Isolation Kit XCF200A-1-SBI 20 reactions   392 € DETAILS


Exosome, Exosomal RNA and circulating cell-free RNA Isolation

Plasma/Serum Exosome Purification and RNA Isolation Mini Kit 58300-NB 50 preps   1141 € DETAILS
Plasma/Serum Exosome Purification and RNA Isolation Midi Kit 58500-NB 25 preps   1272 € DETAILS
Plasma/Serum Exosome Purification and RNA Isolation Maxi Kit 58600-NB 15 preps   1051 € DETAILS
Plasma/Serum Exosome and Free-Circulating RNA Isolation Mini Kit 59500-NB 50 preps   1658 € DETAILS
Plasma/Serum Exosome and Free-Circulating RNA Isolation Midi Kit 59600-NB 25 preps   1491 € DETAILS
Plasma/Serum Exosome and Free-Circulating RNA Isolation Maxi Kit 59700-NB 15 preps   1272 € DETAILS
Plasma/Serum Circulating and Exosomal RNA Purification Mini Kit (Slurry Format), 0.25 - 2 ml sample input 51000-NB 50 preps   542 € DETAILS
Plasma/Serum Circulating and Exosomal RNA Purification Kit (Slurry Format), 0.25 - 5 ml sample input 42800-NB 50 preps   784 € DETAILS
Plasma/Serum Circulating and Exosomal RNA Purification Kit (Slurry Format), 0.25 - 5 ml sample input - CE-marked (for IVD) Dx42800-NB 50 preps   819 € DETAILS
Plasma/Serum Circulating and Exosomal RNA Purification Maxi Kit (Slurry Format), 2 - 5 ml sample input 50900-NB 25 preps   607 € DETAILS
Plasma/Serum Circulating and Exosomal RNA Purification 96-well Kit (Slurry Format), 0.25 - 5 ml sample input 29500-NB 96 preps (1 plate)   674 € DETAILS
Plasma/Serum Circulating and Exosomal RNA and DNA Purification Kit (Slurry Format) Mini, 0.2 - 2ml sample input 53300-NB 50 preps   538 € DETAILS
Plasma/Serum Circulating and Exosomal RNA and DNA Purification Kit (Slurry Format) Maxi, 2 - 5ml sample input 53400-NB 25 preps   597 € DETAILS
Urine Exosome Purification and RNA Isolation Mini Kit 58400-NB 50 preps   1437 € DETAILS
Urine Exosome Purification and RNA Isolation Midi Kit 58700-NB 25 preps   1272 € DETAILS
Urine Exosome Purification and RNA Isolation Maxi Kit 58800-NB 15 preps   1051 € DETAILS
Urine Exosome and Free-Circulating RNA Isolation Mini Kit 59200-NB 50 preps   1658 € DETAILS
Urine Exosome and Free-Circulating RNA Isolation Midi Kit 59300-NB 25 preps   1491 € DETAILS
Urine Exosome and Free-Circulating RNA Isolation Maxi Kit 59400-NB 15 preps   1272 € DETAILS
Exosomal RNA Isolation Kit 58000-NB 50 preps   415 € DETAILS


NGS smallRNA/microRNA Library Preparation

RealSeq-Biofluids NGS Library Preparation Kit for miRNAs and small RNAs, for total RNA samples from biofluids (Illumina Platform), includes size selection reagent 600-00012-SOM 12 rxns   1172 € DETAILS
RealSeq-Biofluids NGS Library Preparation Kit for miRNAs and small RNAs, for total RNA samples from biofluids (Illumina Platform), includes size selection reagent 600-00024-SOM 24 rxns   2073 € DETAILS
RealSeq-Biofluids NGS Library Preparation Kit for miRNAs and small RNAs, for total RNA samples from biofluids (Illumina Platform), includes size selection reagent 600-00048-SOM 48 rxns   3660 € DETAILS


qPCR Kits for the accurate quantification of smallRNAs/microRNAs from biofluids are also offered.

NGS DNA Library Preparation

Accel-NGS 2S PCR-Free Library Kit for Illumina - 24 reactions 20024-SWI 24 rxns   723 € DETAILS
Accel-NGS 2S PCR-Free Library Kit for Illumina - 96 reactions 20096-SWI 96 rxns   2497 € DETAILS
Accel-NGS 2S Plus DNA Library Kit for Illumina - 24 reactions 21024-SWI 24 rxns   774 € DETAILS
Accel-NGS 2S Plus DNA Library Kit for Illumina - 96 reactions 21096-SWI 96 rxns   2702 € DETAILS
Accel-NGS 2S Hyb DNA Library Kit for Illumina - 24 reactions 23024-SWI 24 rxns   723 € DETAILS
Accel-NGS 2S Hyb DNA Library Kit for Illumina - 96 reactions 23096-SWI 96 rxns   2497 € DETAILS
Accel-Amplicon 56G Oncology Panel v2 AL-56248-SWI 48 rxns   4280 € DETAILS
Swift Amplicon 16S+ITS Panel AL-51648-SWI 48 rxns   1287 € DETAILS

To find the NGS DNA Library Preparation Kit optimized for your application, see our Selection Guide

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