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SARS-CoV-2 Inhibitor Screening

With no evidence yet for effective COVID-19 treatments, there is an urgent need for the development of SARS-CoV-2 inhibitors, including vaccines, therapeutic antibodies and small molecular compounds.

Several SARS-CoV-2 inhibitor screening/binding assay kits listed below are based on the interaction between ACE2 protein and SARS-CoV-2 spike protein RBD. They are designed to facilitate the identification and characterization of SARS-CoV-2 inhibitors. These kits are available from our partners ACROBiosystems, Epigentek, and RayBiotech.

Epigentek also released kits which focus on studies of SARS-CoV-2 targeted furin or proprotein convertase (PC) cleavage activity. These first-of-its-kind tools can be used to rapidly detect SARS-CoV-2 targeted PC and facilitated proteases using biological samples as well as screen for inhibitors of these enzymes that cleave SARS-CoV-2 proteins. Subsequent implications can be the effective development of drug candidates or therapeutic treatments.

The product range of RayBiotech consists of enzyme-linked immunosorbent assays (ELISAs) that use a 96-well plate and produce a colorimetric read-out for easy data interpretation. Their binding assays can be used for studying interactions between the SARS-CoV-2 Spike protein (wild-type & variants) and key host cell receptors, including angiotensin I converting enzyme 2 (ACE2), neuropilin-1 (NRP1), and tyrosine-protein kinase receptor UFO (AXL).

 

 

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Description Cat# Size Price    
CoviDrop SARS-CoV-2 Spike-ACE2 Binding Inhibitor Screening Fast Kit D-1004-48-EP 48 Assays 327 € DETAILS   Add to Cart 
CoviDrop SARS-CoV-2 Spike-ACE2 Binding Inhibitor Screening Fast Kit D-1004-96-EP 96 Assays 549 € DETAILS   Add to Cart 
CoviDrop SARS-CoV-2 Spike-ACE2 Binding Activity/Inhibition Assay Kit D-1005-48-EP 48 Assays 327 € DETAILS   Add to Cart 
CoviDrop SARS-CoV-2 Spike-ACE2 Binding Activity/Inhibition Assay Kit D-1005-96-EP 96 Assays 549 € DETAILS   Add to Cart 
CoviDrop SARS-CoV-2 Specific Furin Cleavage Site (Wild Type) Blocker/Inhibitor Screening Kit  D-1009-096-EP 96 Assays 465 € DETAILS   Add to Cart 
CoviDrop SARS-CoV-2 Specific Furin Cleavage Site (Wild Type) Blocker/Inhibitor Screening Kit  D-1009-192-EP 192 Assays 795 € DETAILS   Add to Cart 
CoviDrop SARS-CoV-2 Specific Furin Cleavage Site (P681R Mutation) Blocker/Inhibitor Screening Kit  D-1010-096-EP 96 Assays 465 € DETAILS   Add to Cart 
CoviDrop SARS-CoV-2 Specific Furin Cleavage Site (P681R Mutation) Blocker/Inhibitor Screening Kit  D-1010-192-EP 192 Assays 795 € DETAILS   Add to Cart 
CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Inhibitor Screening Fast Kit D-1006-48-EP 48 Assays 349 € DETAILS   Add to Cart 
CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Inhibitor Screening Fast Kit D-1006-96-EP 96 Assays 572 € DETAILS   Add to Cart 
CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Activity/Inhibition Assay Kit D-1007-48-EP 48 Assays 349 € DETAILS   Add to Cart 
CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Activity/Inhibition Assay Kit D-1007-96-EP 96 Assays 572 € DETAILS   Add to Cart 
COVID-19 Spike-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SACE2-1-RB 1 x 96-Well Strip Microplate Kit
Special

450.00 €
DETAILS   Add to Cart 
COVID-19 Spike-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SACE2-2-RB 2 x 96-Well Strip Microplate Kit
Special

784.50 €
DETAILS   Add to Cart 
COVID-19 Spike-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SACE2-5-RB 5 x 96-Well Strip Microplate Kit
Special

1704.00 €
DETAILS   Add to Cart 
COVID-19 Spike-ACE2 Binding Assay Kit (ACE2-coated plates) CoV-ACE2S2-1-RB 1 x 96-Well Strip Microplate Kit
Special

450.00 €
DETAILS   Add to Cart 
COVID-19 Spike-ACE2 Binding Assay Kit (ACE2-coated plates) CoV-ACE2S2-2-RB 2 x 96-Well Strip Microplate Kit
Special

784.50 €
DETAILS   Add to Cart 
COVID-19 Spike-ACE2 Binding Assay Kit (ACE2-coated plates) CoV-ACE2S2-5-RB 5 x 96-Well Strip Microplate Kit
Special

1704.00 €
DETAILS   Add to Cart 
COVID-19 Spike-NRP1 Binding Assay Kit (NRP1-coated plates) CoV-NRP1S1-1-RB 1 x 96-Well Strip Microplate Kit
Special

450.00 €
DETAILS   Add to Cart 
COVID-19 Spike-NRP1 Binding Assay Kit (NRP1-coated plates) CoV-NRP1S1-2-RB 2 x 96-Well Strip Microplate Kit
Special

784.50 €
DETAILS   Add to Cart 
COVID-19 Spike-NRP1 Binding Assay Kit (NRP1-coated plates) CoV-NRP1S1-5-RB 5 x 96-Well Strip Microplate Kit
Special

1704.00 €
DETAILS   Add to Cart 
COVID-19 Spike-CendR-NRP1 Binding Assay Kit (S1CendR-coated plates) CoV-CendR-NRP1-1-RB 1 x 96-Well Strip Microplate Kit
Special

450.00 €
DETAILS   Add to Cart 
COVID-19 Spike-CendR-NRP1 Binding Assay Kit (S1CendR-coated plates) CoV-CendR-NRP1-2-RB 2 x 96-Well Strip Microplate Kit
Special

784.50 €
DETAILS   Add to Cart 
COVID-19 Spike-CendR-NRP1 Binding Assay Kit (S1CendR-coated plates) CoV-CendR-NRP1-5-RB 5 x 96-Well Strip Microplate Kit
Special

1704.00 €
DETAILS   Add to Cart 
COVID-19 Spike-AXL Binding Assay Kit (AXL-coated plates) CoV-AXLS1-1-RB 1 x 96-Well Strip Microplate Kit
Special

450.00 €
DETAILS   Add to Cart 
COVID-19 Spike-AXL Binding Assay Kit (AXL-coated plates) CoV-AXLS1-2-RB 2 x 96-Well Strip Microplate Kit
Special

784.50 €
DETAILS   Add to Cart 
COVID-19 Spike-AXL Binding Assay Kit (AXL-coated plates) CoV-AXLS1-5-RB 5 x 96-Well Strip Microplate Kit
Special

1704.00 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (D614G)-ACE2 Binding Assay Kit (ACE2-coated plates) CoV-ACE2SM6-1-RB 1 x 96-Well Strip Microplate Kit
Special

495.00 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (D614G)-ACE2 Binding Assay Kit (ACE2-coated plates) CoV-ACE2SM6-2-RB 2 x 96-Well Strip Microplate Kit
Special

858.75 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (D614G)-ACE2 Binding Assay Kit (ACE2-coated plates) CoV-ACE2SM6-5-RB 5 x 96-Well Strip Microplate Kit
Special

1856.25 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (HV69-70del, N501Y, D614G - B.1.1.7)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM1ACE2-1-RB 1 x 96-Well Strip Microplate Kit
Special

495.00 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (HV69-70del, N501Y, D614G - B.1.1.7)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM1ACE2-2-RB 2 x 96-Well Strip Microplate Kit
Special

858.75 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (HV69-70del, N501Y, D614G - B.1.1.7)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM1ACE2-5-RB 5 x 96-Well Strip Microplate Kit
Special

1856.25 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (N501Y)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM2ACE2-1-RB 1 x 96-Well Strip Microplate Kit
Special

495.00 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (N501Y)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM2ACE2-2-RB 2 x 96-Well Strip Microplate Kit
Special

858.75 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (N501Y)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM2ACE2-5-RB 5 x 96-Well Strip Microplate Kit
Special

1856.25 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (E484K)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM3ACE2-1-RB 1 x 96-Well Strip Microplate Kit
Special

495.00 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (E484K)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM3ACE2-2-RB 2 x 96-Well Strip Microplate Kit
Special

858.75 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (E484K)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM3ACE2-5-RB 5 x 96-Well Strip Microplate Kit
Special

1856.25 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (K417N, E484K, N501Y - B.1.351)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM4ACE2-1-RB 1 x 96-Well Strip Microplate Kit
Special

495.00 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (K417N, E484K, N501Y - B.1.351)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM4ACE2-2-RB 2 x 96-Well Strip Microplate Kit
Special

858.75 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (K417N, E484K, N501Y - B.1.351)-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM4ACE2-5-RB 5 x 96-Well Strip Microplate Kit
Special

1856.25 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (K417T, E484K, N501Y - P.1 )-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM5ACE2-1-RB 1 x 96-Well Strip Microplate Kit
Special

495.00 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (K417T, E484K, N501Y - P.1 )-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM5ACE2-2-RB 2 x 96-Well Strip Microplate Kit
Special

858.75 €
DETAILS   Add to Cart 
COVID-19 Spike Variant (K417T, E484K, N501Y - P.1 )-ACE2 Binding Assay Kit (Spike RBD-coated plates) CoV-SM5ACE2-5-RB 5 x 96-Well Strip Microplate Kit
Special

1856.25 €
DETAILS   Add to Cart 
SARS-CoV-2 S1 Protein-ACE2 Binding Inhibitor Screening Kit K2050-100-BV 100 assays 733 € DETAILS   Add to Cart 
SARS-CoV-2 (B.1.1.7) Inhibitor Screening Kit (Spike RBD) EP-108-96tests-AC 96tests 785 € DETAILS   Add to Cart 
SARS-CoV-2 (B.1.351) Inhibitor Screening Kit (Spike RBD) EP-109-96tests-AC 96tests 785 € DETAILS   Add to Cart 
SARS-CoV-2 (B.1.617.2) Inhibitor Screening Kit (Spike RBD) EP-111-96tests-AC 96tests 785 € DETAILS   Add to Cart 
SARS-CoV-2 (P.1) Inhibitor Screening Kit (Spike RBD) EP-110-96tests-AC 96tests 785 € DETAILS   Add to Cart 
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