SARS-CoV-2 Inhibitor Screening
With no evidence yet for effective COVID-19 treatments, there is an urgent need for the development of SARS-CoV-2 inhibitors, including vaccines, therapeutic antibodies and small molecular compounds.Several SARS-CoV-2 inhibitor screening/binding assay kits listed below are based on the interaction between ACE2 protein and SARS-CoV-2 spike protein RBD. They are designed to facilitate the identification and characterization of SARS-CoV-2 inhibitors. These kits are available from our partners ACROBiosystems, Epigentek, and RayBiotech.
Epigentek recently released two kits which focus on studies of SARS-CoV-2 targeted furin or proprotein convertase (PC) cleavage activity. These first-of-its-kind tools can be used to rapidly detect SARS-CoV-2 targeted PC and facilitated proteases using biological samples as well as screen for inhibitors of these enzymes that cleave SARS-CoV-2 proteins. Subsequent implications can be the effective development of drug candidates or therapeutic treatments.
The first kit, CoviDrop(TM) SARS-CoV-2 Targeted Proprotein Convertase Inhibitor Screening Fast Kit (Catalog No. D-1006), screens for inhibitors of SARS-CoV-2 targeted furin and PCs. The second kit, CoviDrop(TM) SARS-CoV-2 Targeted Proprotein Convertase Activity/Inhibition Assay Kit (Catalog No. D-1007), quantitatively measures the activity or inhibition levels of furin or furin-like PC as well as facilitated proteases in biological samples such as nasal swabs.
| Description | Cat# | Size | Price | ||
|---|---|---|---|---|---|
| CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Inhibitor Screening Fast Kit | D-1006-48-EP | 48 Assays | 349 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Inhibitor Screening Fast Kit | D-1006-96-EP | 96 Assays | 572 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Activity/Inhibition Assay Kit | D-1007-48-EP | 48 Assays | 349 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Activity/Inhibition Assay Kit | D-1007-96-EP | 96 Assays | 572 € | DETAILS | Add to Cart |
| SARS-CoV-2 Inhibitor Screening Kit | EP-105-96tests-AC | 96 tests | 731 € | DETAILS | Add to Cart |
| SARS-CoV-2 Inhibitor Screening Kit | EP-105-480tests-AC | 480 tests | 2369 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SACE2-1-RB | 1 x 96-Well Strip Microplate Kit | 600 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SACE2-2-RB | 2 x 96-Well Strip Microplate Kit | 1046 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SACE2-5-RB | 5 x 96-Well Strip Microplate Kit | 2272 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (ACE2-coated plates) | CoV-ACE2S2-1-RB | 1 x 96-Well Strip Microplate Kit | 600 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (ACE2-coated plates) | CoV-ACE2S2-2-RB | 2 x 96-Well Strip Microplate Kit | 1046 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (ACE2-coated plates) | CoV-ACE2S2-5-RB | 5 x 96-Well Strip Microplate Kit | 2272 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Spike-ACE2 Binding Inhibitor Screening Fast Kit | D-1004-48-EP | 48 Assays | 327 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Spike-ACE2 Binding Inhibitor Screening Fast Kit | D-1004-96-EP | 96 Assays | 549 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Spike-ACE2 Binding Activity/Inhibition Assay Kit | D-1005-48-EP | 48 Assays | 327 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Spike-ACE2 Binding Activity/Inhibition Assay Kit | D-1005-96-EP | 96 Assays | 549 € | DETAILS | Add to Cart |
| SARS-CoV-2 S1 Protein-ACE2 Binding Inhibitor Screening Kit | K2050-100-BV | 100 assays | 733 € | DETAILS | Add to Cart |
