SARS-CoV-2 Inhibitor Screening
With no evidence yet for effective COVID-19 treatments, there is an urgent need for the development of SARS-CoV-2 inhibitors, including vaccines, therapeutic antibodies and small molecular compounds.Several SARS-CoV-2 inhibitor screening/binding assay kits listed below are based on the interaction between ACE2 protein and SARS-CoV-2 spike protein RBD. They are designed to facilitate the identification and characterization of SARS-CoV-2 inhibitors. These kits are available from our partners ACROBiosystems, Epigentek, and RayBiotech.
Epigentek also released kits which focus on studies of SARS-CoV-2 targeted furin or proprotein convertase (PC) cleavage activity. These first-of-its-kind tools can be used to rapidly detect SARS-CoV-2 targeted PC and facilitated proteases using biological samples as well as screen for inhibitors of these enzymes that cleave SARS-CoV-2 proteins. Subsequent implications can be the effective development of drug candidates or therapeutic treatments.
The product range of RayBiotech consists of enzyme-linked immunosorbent assays (ELISAs) that use a 96-well plate and produce a colorimetric read-out for easy data interpretation. Their binding assays can be used for studying interactions between the SARS-CoV-2 Spike protein (wild-type & variants) and key host cell receptors, including angiotensin I converting enzyme 2 (ACE2), neuropilin-1 (NRP1), and tyrosine-protein kinase receptor UFO (AXL).
| Description | Cat# | Size | Price | ||
|---|---|---|---|---|---|
| CoviDrop SARS-CoV-2 Spike-ACE2 Binding Inhibitor Screening Fast Kit | D-1004-48-EP | 48 Assays | 350 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Spike-ACE2 Binding Inhibitor Screening Fast Kit | D-1004-96-EP | 96 Assays | 583 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Spike-ACE2 Binding Activity/Inhibition Assay Kit | D-1005-48-EP | 48 Assays | 343 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Spike-ACE2 Binding Activity/Inhibition Assay Kit | D-1005-96-EP | 96 Assays | 572 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Specific Furin Cleavage Site (Wild Type) Blocker/Inhibitor Screening Kit | D-1009-096-EP | 96 Assays | 471 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Specific Furin Cleavage Site (Wild Type) Blocker/Inhibitor Screening Kit | D-1009-192-EP | 192 Assays | 801 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Specific Furin Cleavage Site (P681R Mutation) Blocker/Inhibitor Screening Kit | D-1010-096-EP | 96 Assays | 471 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Specific Furin Cleavage Site (P681R Mutation) Blocker/Inhibitor Screening Kit | D-1010-192-EP | 192 Assays | 801 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Inhibitor Screening Fast Kit | D-1006-48-EP | 48 Assays | 366 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Inhibitor Screening Fast Kit | D-1006-96-EP | 96 Assays | 596 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Activity/Inhibition Assay Kit | D-1007-48-EP | 48 Assays | 366 € | DETAILS | Add to Cart |
| CoviDrop SARS-CoV-2 Targeted Proprotein Convertase Activity/Inhibition Assay Kit | D-1007-96-EP | 96 Assays | 596 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SACE2-1-RB | 1 x 96-Well Strip Microplate Kit | 600 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SACE2-2-RB | 2 x 96-Well Strip Microplate Kit | 1046 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SACE2-5-RB | 5 x 96-Well Strip Microplate Kit | 2272 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (ACE2-coated plates) | CoV-ACE2S2-1-RB | 1 x 96-Well Strip Microplate Kit | 600 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (ACE2-coated plates) | CoV-ACE2S2-2-RB | 2 x 96-Well Strip Microplate Kit | 1046 € | DETAILS | Add to Cart |
| COVID-19 Spike-ACE2 Binding Assay Kit (ACE2-coated plates) | CoV-ACE2S2-5-RB | 5 x 96-Well Strip Microplate Kit | 2272 € | DETAILS | Add to Cart |
| COVID-19 Spike-NRP1 Binding Assay Kit (NRP1-coated plates) | CoV-NRP1S1-1-RB | 1 x 96-Well Strip Microplate Kit | 600 € | DETAILS | Add to Cart |
| COVID-19 Spike-NRP1 Binding Assay Kit (NRP1-coated plates) | CoV-NRP1S1-2-RB | 2 x 96-Well Strip Microplate Kit | 1046 € | DETAILS | Add to Cart |
| COVID-19 Spike-NRP1 Binding Assay Kit (NRP1-coated plates) | CoV-NRP1S1-5-RB | 5 x 96-Well Strip Microplate Kit | 2272 € | DETAILS | Add to Cart |
| COVID-19 Spike-CendR-NRP1 Binding Assay Kit (S1CendR-coated plates) | CoV-CendR-NRP1-1-RB | 1 x 96-Well Strip Microplate Kit | 600 € | DETAILS | Add to Cart |
| COVID-19 Spike-CendR-NRP1 Binding Assay Kit (S1CendR-coated plates) | CoV-CendR-NRP1-2-RB | 2 x 96-Well Strip Microplate Kit | 1046 € | DETAILS | Add to Cart |
| COVID-19 Spike-CendR-NRP1 Binding Assay Kit (S1CendR-coated plates) | CoV-CendR-NRP1-5-RB | 5 x 96-Well Strip Microplate Kit | 2272 € | DETAILS | Add to Cart |
| COVID-19 Spike-AXL Binding Assay Kit (AXL-coated plates) | CoV-AXLS1-1-RB | 1 x 96-Well Strip Microplate Kit | 600 € | DETAILS | Add to Cart |
| COVID-19 Spike-AXL Binding Assay Kit (AXL-coated plates) | CoV-AXLS1-2-RB | 2 x 96-Well Strip Microplate Kit | 1046 € | DETAILS | Add to Cart |
| COVID-19 Spike-AXL Binding Assay Kit (AXL-coated plates) | CoV-AXLS1-5-RB | 5 x 96-Well Strip Microplate Kit | 2272 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (D614G)-ACE2 Binding Assay Kit (ACE2-coated plates) | CoV-ACE2SM6-1-RB | 1 x 96-Well Strip Microplate Kit | 660 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (D614G)-ACE2 Binding Assay Kit (ACE2-coated plates) | CoV-ACE2SM6-2-RB | 2 x 96-Well Strip Microplate Kit | 1145 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (D614G)-ACE2 Binding Assay Kit (ACE2-coated plates) | CoV-ACE2SM6-5-RB | 5 x 96-Well Strip Microplate Kit | 2475 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (HV69-70del, N501Y, D614G - B.1.1.7)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM1ACE2-1-RB | 1 x 96-Well Strip Microplate Kit | 660 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (HV69-70del, N501Y, D614G - B.1.1.7)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM1ACE2-2-RB | 2 x 96-Well Strip Microplate Kit | 1145 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (HV69-70del, N501Y, D614G - B.1.1.7)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM1ACE2-5-RB | 5 x 96-Well Strip Microplate Kit | 2475 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (N501Y)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM2ACE2-1-RB | 1 x 96-Well Strip Microplate Kit | 660 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (N501Y)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM2ACE2-2-RB | 2 x 96-Well Strip Microplate Kit | 1145 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (N501Y)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM2ACE2-5-RB | 5 x 96-Well Strip Microplate Kit | 2475 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (E484K)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM3ACE2-1-RB | 1 x 96-Well Strip Microplate Kit | 660 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (E484K)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM3ACE2-2-RB | 2 x 96-Well Strip Microplate Kit | 1145 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (E484K)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM3ACE2-5-RB | 5 x 96-Well Strip Microplate Kit | 2475 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (K417N, E484K, N501Y - B.1.351)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM4ACE2-1-RB | 1 x 96-Well Strip Microplate Kit | 660 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (K417N, E484K, N501Y - B.1.351)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM4ACE2-2-RB | 2 x 96-Well Strip Microplate Kit | 1145 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (K417N, E484K, N501Y - B.1.351)-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM4ACE2-5-RB | 5 x 96-Well Strip Microplate Kit | 2475 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (K417T, E484K, N501Y - P.1 )-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM5ACE2-1-RB | 1 x 96-Well Strip Microplate Kit | 660 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (K417T, E484K, N501Y - P.1 )-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM5ACE2-2-RB | 2 x 96-Well Strip Microplate Kit | 1145 € | DETAILS | Add to Cart |
| COVID-19 Spike Variant (K417T, E484K, N501Y - P.1 )-ACE2 Binding Assay Kit (Spike RBD-coated plates) | CoV-SM5ACE2-5-RB | 5 x 96-Well Strip Microplate Kit | 2475 € | DETAILS | Add to Cart |
| SARS-CoV-2 S1 Protein-ACE2 Binding Inhibitor Screening Kit | K2050-100-BV | 100 assays | please inquire € | DETAILS | Add to Cart |
| SARS-CoV-2 (B.1.1.529, Omicron) Inhibitor Screening Kit (Spike RBD) | EP-115-96tests-AC | 96tests | 785 € | DETAILS | Add to Cart |
| SARS-CoV-2 (B.1.1.7) Inhibitor Screening Kit (Spike RBD) | EP-108-96tests-AC | 96tests | 785 € | DETAILS | Add to Cart |
| SARS-CoV-2 (B.1.351) Inhibitor Screening Kit (Spike RBD) | EP-109-96tests-AC | 96tests | 785 € | DETAILS | Add to Cart |
| SARS-CoV-2 (B.1.617.2) Inhibitor Screening Kit (Spike RBD) | EP-111-96tests-AC | 96tests | 785 € | DETAILS | Add to Cart |
