Home -> Genomics -> Nucleosomes -> Recombinant Nucleosomes (Oncogenic Amino Acid Substitutions)

Recombinant Nucleosomes (Oncogenic Amino Acid Substitutions)

• Low lot-to-lot variability and high purity
• Physiologically relevant substrates in enzyme screening assays and effector protein binding experiments with nucleosomes incorporating various histone amino acid substitutions
• Free from DNA which could alter assayed conditions
• No post-translational histone modifications - ideal for conducting enzyme activity and screening assays.
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EpiCypher´s recombinant mononucleosomes are assembled from recombinant human histones expressed in E. coli (two each of histones H2A, H2B, H3 and H4, but with one of the histones expressed as a variant with an oncogenic amino acid substitution), wrapped by 147 bases of 601 positioning (Widom) sequence DNA.

 

 

Description Cat# Size Price    
Mononucleosomes (H3.3 K27M), Recombinant Human 16-0323-EPC 100 ug 485 € DETAILS   Add to Cart 
Mononucleosomes (H3.3 K27M), Recombinant Human, Biotinylated 16-1323-EPC 50 ug 540 € DETAILS   Add to Cart 
Mononucleosomes (H3.3 K4M), Recombinant Human Biotinylated 16-0349-EPC 50 ug 540 € DETAILS   Add to Cart 
Mononucleosomes (H3.3 K9M), Recombinant Human Biotinylated 16-0350-EPC 50 ug 540 € DETAILS   Add to Cart 
Mononucleosomes (H3.3 G34V), Recombinant Human Biotinylated 16-0347-EPC 50 ug 540 € DETAILS   Add to Cart 
Mononucleosomes (H3.3 G34W), Recombinant Human Biotinylated 16-0348-EPC 50 ug 540 € DETAILS   Add to Cart 
Mononucleosomes (H3.3 K36M), Recombinant Human Biotinylated 16-0344-EPC 50 ug 540 € DETAILS   Add to Cart 

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