BioCat GmbH • Im Neuenheimer Feld 584 • D-69120 Heidelberg • Tel.: +49(0)6221 7141516
Home -> Genomics -> Methylated Histone Target Screening

Methylated Histone Target Screening

• The fastest procedure available - finished within 5 hours
• Strip microwell format makes the assay flexible: manual or high throughput
• Columns for DNA purification are included: save time and reduce labor
• Compatible with all subsequent DNA amplification-based approaches and with DNA array analysis
• Simple, reliable, and consistent assay conditions

The positions of histone H3 at lysine 4 and 9 (H3-K4 and H3-K9) are important for epigenetic transcriptional regulation as they can be either methylated or acetylated.
Methylated H3-K4 and H3-K9 are involved in tumorigenesis through inactivation of tumor suppression genes. Thus, identification of genes silenced through H3-K4 and H3-K9 methylation are of particluar significance for understanding and analyzing biological normal and pathological processes.

Chromatin Immunoprecipitation (ChIP) is a powerful technique for studying protein-DNA interaction in vivo: H3-K4 and H3-K9 ChIP enable you to identify genes silenced by methylated histones.
Epigentek´s H3-K4 and H3-K9 ChIP kits are complete, fast and easy-to-use kits including DNA purification columns. They are available in special versions when using tissue samples as source material.

Image
Related Links

Histone Peptide Substrates


BioCat Summer Special

Summer Special

10% OFF
Norgen Sample Preparation Kits

Electrophoresis

30% OFF BioCat Universal Agarose

DNA and RNA Purification

Bioline

Use ISOLATE II Nucleic Acid Isolation Kits for the purification of high-quality DNA and RNA.

Email Newsletter

Subscribe to the BioCat Email Newsletter.

Clone Resources

BioCat Clone Resources

Browse two of the most renowned clone resources of full-length cDNA, ORF, and shRNA clones as well as siRNA and yeast knockout strains.

Genome Engineering

Genome Engineering

Use the CRISPR/Cas9 SmartNuclease System to edit the genome.

ExoQuick and ExoQuick-TC

ExoQuick Exosome Isolation

Benefit from the most cited exosome isolation reagent for efficient exosome isolation and exosomal RNA purification from biofluids or culture media.

Home
Imprint / Impressum | Privacy Policy / Datenschutzerklärung
Top of Page Up!