Genome Engineering
- Cas13a ELISA Kits
- Cas9 Activity Assays
- Cas9 Expressing Cell Lines
- Cas9 Protein with Nuclear Localization Signal
- Cas9 Quantitation
- CRISPR Cas9 AAVS1 Safe Harbor Knockin System
- CRISPR Cas9 AAVS1 Safe Harbor Targeting System
- CRISPR Cas9 Guide RNA Custom Constructs
- CRISPR Cas9 Lentiviral Guide RNA Cloning Vectors and Control Constructs
- CRISPR Cas9 Lentiviral Guide RNA Custom Constructs and Libraries
- CRISPR Cas9 Lentiviral Guide RNA Libraries with expressed barcodes for RNA-Seq / Perturb-Seq
- CRISPR Cas9 Lentiviral Guide RNA Premade Libraries
- CRISPR Cas9 Lentiviral sgRNA Premade Particles
- CRISPR Cas9 Multiplex Guide RNA Cloning Kits
- CRISPR Cas9 pCAS-Guide Genome Engineering System: Gene-specific Ready-to-Go Knockout Kits
- CRISPR Cas9 pCAS-Guide Genome Engineering System: Vector-based
- CRISPR Cas9 ROSA26 Safe Harbor Targeting System
- CRISPR Cas9 SmartNuclease Genome Engineering System: AAV vector-based for in vivo applications
- CRISPR Cas9 SmartNuclease Genome Engineering System: Lentiviral Vector-based
- CRISPR Cas9 SmartNuclease Genome Engineering System: RNA-based for in vivo applications
- CRISPR Cas9 SmartNuclease Genome Engineering System: Vector-based
- CRISPR Cas9 transEDIT Genome Engineering System: Cas9 Nuclease and Nickase Expression Vectors
- CRISPR Cas9 transEDIT Genome Engineering System: gRNA Cloning Vectors and Negative Controls
- CRISPR Cas9 transEDIT Genome Engineering System: gRNA Target Gene Sets
- CRISPR Cas9 transEDIT Genome Engineering System: Pooled gRNA Libraries
- CRISPR Cas9 transEDIT-dual Genome Engineering System: Dual gRNA Target Gene Sets
- CRISPR Cas9 transEDIT-dual Genome Engineering System: Negative and Positive Controls
- CRISPR/CAS9 Antibodies
- CRISPR/CAS9 RT-PCR Primers
- CRISPRa Expressing Cell Lines
- CRISPRa Lentiviral Guide RNA Premade Libraries
- CRISPRi Expressing Cell Lines
- CRISPRi Lentiviral Guide RNA Premade Libraries
- crRNA Oligo Template Synthesis
- crRNA Synthesis and Screening
- Custom Clonal Gene Knockout/Editing Cell Line Engineering
- Custom Genome Engineering
- Custom Knockout Cell Line Engineering
- gRNA Synthesis Kits (IVT-based)
- Homologous Recombination Targeting Vectors
- Indel Detection
- Recombinant CAS9 Nucleases and Nickases
- Recombinant Cpf1 Nucleases
- sgRNA expressing Lentivirus Controls for Cas9 Cell Lines
- Site-specific Chromatin Loop Formation by dCas9
- ssODN-mediated CRISPR Cas9 System for Gene Deletion, Mutation or Tagging
- Synthetic sgRNA
- TALE-Nuclease AAVS1 Targeting
- Transcriptional Activation of endogenous genes by CRISPR/Cas9 SAM
- Transcriptional Activation of endogenous genes by dCas9-VPH
- Transcriptional Repression of endogenous genes by dCas9-KRAB
Genome editing technologies using engineered, site-specific nucleases including designer Transcription Activator-Like Effector Nucleases (TALENs) and Cas9/CRISPR-mediated multiplex Genome editing abilities have revolutionized the field of engineering target genomes.
These designed nucleases, when used in combination with Homologous Recombination (HR) targeting vectors, now enable gene knock-outs, knock-ins and even single base Genome editing on demand.
