Genome Engineering

• Cas9 Activity Assays
• Cas9 Protein with Nuclear Localization Signal
• CRISPR Cas9 AAVS1 Safe Harbor Knockin System
• CRISPR Cas9 AAVS1 Safe Harbor Targeting System
• CRISPR Cas9 Lentiviral sgRNA Premade Particles
• CRISPR Cas9 Multiplex Guide RNA Cloning Kits
• CRISPR Cas9 pCAS-Guide Genome Engineering System: Vector-based
• CRISPR Cas9 Retroviral Cloning Vectors
• CRISPR Cas9 ROSA26 Safe Harbor Targeting System
• CRISPR Cas9 SmartNuclease Genome Engineering System: AAV vector-based for in vivo applications
• CRISPR Cas9 SmartNuclease Genome Engineering System: Lentiviral Vector-based
• CRISPR Cas9 SmartNuclease Genome Engineering System: RNA-based for in vivo applications
• CRISPR Cas9 SmartNuclease Genome Engineering System: Vector-based
• CRISPR Human sgRNA Libraries for Gene Knockout
• CRISPR/CAS9 Antibodies
• CRISPR/CAS9 RT-PCR Primers
• crRNA Oligo Template Synthesis
• Gene Editing Quantitation
• Homologous Recombination Targeting Vectors
• Indel Detection
• sgRNA expressing Lentivirus Controls for Cas9 Cell Lines
• TALE-Nuclease AAVS1 Targeting
• Transcriptional Activation of endogenous genes by CRISPR/Cas9 SAM

Powerful Tools for Engineering Genomes
Genome editing technologies using engineered, site-specific nucleases including designer Transcription Activator-Like Effector Nucleases (TALENs) and Cas9/CRISPR-mediated multiplex Genome editing abilities have revolutionized the field of engineering target genomes.
These designed nucleases, when used in combination with Homologous Recombination (HR) targeting vectors, now enable gene knock-outs, knock-ins and even single base Genome editing on demand.