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Circulating DNA Isolation

Plasma/Serum and Urine Circulating DNA Isolation Kits

The Norgen Cell-Free Circulating (CFC) DNA Purification Kits provide an efficient method for the purification of fragmented free-circulating DNA or total nucleic acids from variable volumes of plasma/serum or cell-free urine samples. The kits are able to isolate all sizes of circulating DNA irrespective of size or GC content, without bias. They provide an advantage over other available kits in that they do not require extension tubes for the purification of cfc DNA from large sample volumes. The purified cfc DNA are eluted in an elution solution that is compatible with all downstream applications including PCR, qPCR, methylation-sensitive PCR, and sequencing.

• Isolate all sizes of cfc-DNA
• Various sample types: Plasma/Serum, Urine, CSF and other bodily fluids
• Concentrate circulating DNA into a flexible elution volume ranging from 10-100ul
• No phenol extractions nor carrier RNA
• Inhibitor-free cfc-DNA
• Versatile input volumes
• 4 different cfc DNA isolation kit sizes available for plasma/serum input:
Mini: 200 ul - 500 ul
Micro: 100 ul - 200 ul
Midi: 1ml - 4ml
Maxi: 5ml - 10ml

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Superior Recovery of Small DNA Fragments from Plasma. Different commercial kits for the purification of cell-free circulating DNA were compared. Using the Norgen Cell-Free Circulating (CFC) DNA Purification Kits (Silicon Carbide), high yields of cfc DNA of all sizes can be isolated. For DNA fragments <150 bp the Norgen kit shows the best recovery.
Data from Diefenbach RJ et al. (2018) Evaluation of commercial kits for purification of circulating free DNA. Cancer Genetics 228-229:21-27.

Cell-Free Circulating (CFC) RNA Purification Kits developed by Norgen are also available.


There are more kits available from other suppliers for isolation of cell-free DNA using magnetic beads (SBI and Epigentek) or silica-coated paramagnetic particles (BioChain). For details check products listed below.
Related Links

Low Abundance DNA Quantification Kit
Plasma/Serum RNA Purification Kits
Plasma/Serum RNA/DNA Purification Mini Kit
Overview plasma/serum sample preparation kits

 

 

Description Cat# Size Price    
Plasma/Serum Cell-Free Circulating DNA (cfc DNA, ccf DNA) Purification Mini Kit 55100-NB 50 preps
Special

355.30 €
DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating DNA Purification Mini Kit - CE-marked (for IVD) Dx55100-NB 50 preps 481 € DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating DNA (cfc DNA, ccf DNA) Purification Mini Kit - Trial Size 55140-NB 4 preps 27 € DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating DNA (cfc DNA, ccf DNA) Purification Micro Kit 55500-NB 50 preps
Special

293.25 €
DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating DNA Purification Micro Kit - CE-marked (for IVD) Dx55500-NB 50 preps 392 € DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating DNA (cfc DNA, ccf DNA) Purification Midi Kit 55600-NB 20 preps
Special

390.15 €
DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating DNA (cfc DNA, ccf DNA) Purification Midi Kit - Trial Size 55640-NB 2 preps 47 € DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating DNA Purification Midi Kit - CE-marked (for IVD) Dx55600-NB 20 preps 495 € DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating DNA (cfc DNA, ccf DNA) Purification Maxi Kit 55800-NB 10 preps
Special

252.45 €
DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating DNA Purification Maxi Kit - CE-marked (for IVD) Dx55800-NB 10 preps 336 € DETAILS   Add to Cart 
Plasma/Serum Circulating DNA Isolation Mini Kit (Slurry Format) 50600-NB 50 preps
Special

243.95 €
DETAILS   Add to Cart 
Plasma/Serum Circulating DNA Isolation Midi Kit (Slurry Format) 51200-NB 20 preps
Special

256.70 €
DETAILS   Add to Cart 
Plasma/Serum Circulating DNA Isolation Maxi Kit (Slurry Format) 51300-NB 10 preps
Special

234.60 €
DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating and Viral Nucleic Acid Purification Maxi Kit 56500-NB 10 preps
Special

263.50 €
DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating and Viral Nucleic Acid Purification Midi Kit 56400-NB 20 preps
Special

400.35 €
DETAILS   Add to Cart 
Plasma/Serum Cell-Free Circulating and Viral Nucleic Acid Purification Mini Kit 56300-NB 50 preps
Special

484.50 €
DETAILS   Add to Cart 
Urine Cell-Free Circulating DNA Purification Mini Kit 56600-NB 50 preps
Special

423.30 €
DETAILS   Add to Cart 
Urine Cell-Free Circulating DNA Purification Midi Kit 56700-NB 20 preps
Special

408.85 €
DETAILS   Add to Cart 
Urine Cell-Free Circulating DNA Purification Maxi Kit 56800-NB 10 preps
Special

263.50 €
DETAILS   Add to Cart 
Urine Cell-Free Circulating and Viral Nucleic Acid Purification Maxi Kit 60100-NB 10 preps
Special

253.30 €
DETAILS   Add to Cart 
Urine Cell-Free Circulating and Viral Nucleic Acid Purification Midi Kit 60000-NB 20 preps
Special

394.40 €
DETAILS   Add to Cart 
Urine Cell-Free Circulating and Viral Nucleic Acid Purification Mini Kit 59900-NB 50 preps
Special

432.65 €
DETAILS   Add to Cart 
EpiQuik Circulating Cell-Free DNA (cf DNA, cfc DNA) Isolation Kit (magnetic-bead based) for isolating cfDNA from 0.5 ml Plasma/Serum P-1064-25-EP 25 preps 225 € DETAILS   Add to Cart 
EpiQuik Circulating Cell-Free DNA (cf DNA, cfc DNA) Isolation Kit (magnetic-bead based) for isolating cfDNA from 0.5 ml Plasma/Serum P-1064-50-EP 50 preps 313 € DETAILS   Add to Cart 
EpiQuik Circulating Cell-Free DNA (cf DNA, cfc DNA) Isolation Easy Kit (magnetic-bead based) for isolating cfDNA from 0.5 ml Plasma/Serum P-1065-25-EP 25 preps 225 € DETAILS   Add to Cart 
EpiQuik Circulating Cell-Free DNA (cf DNA, cfc DNA) Isolation Easy Kit (magnetic-bead based) for isolating cfDNA from 0.5 ml Plasma/Serum P-1065-50-EP 50 preps 313 € DETAILS   Add to Cart 
cfMAX cfDNA Isolation System for high yields of cfDNA CFMAX100A-1-SBI 1 kit (processing of 80ml serum/plasma) 478 € DETAILS   Add to Cart 
cfPure V2 Cell Free DNA Extraction Kit (magnetic bead-based, automatization-friendly) for human plasma/serum K5011610-V2-BC 100ml sample volume 524 € DETAILS   Add to Cart 
cfPure V2 Cell Free DNA Extraction Kit (magnetic bead-based, automatization-friendly) for human plasma/serum K5011625-V2-BC 250ml sample volume 747 € DETAILS   Add to Cart 
cfPure Max V2 Cell Free DNA Extraction Kit (magnetic bead-based, automatization-friendly) for human plasma/serum, sample volumes >5ml K5011625MA-V2-BC 250ml sample volume 564 € DETAILS   Add to Cart 
cfPure MAX Cell-Free DNA Extraction Kit K5011625MA-BC 250ml sample volume 564 € DETAILS   Add to Cart 
DNA Cleared Plasma DCP100A-1-SBI 100 ml 480 € DETAILS   Add to Cart 
Plasma/Serum cfc-DNA Advanced Purification Kit 68000-NB 50 preps
Special

1105.00 €
DETAILS   Add to Cart 
Plasma/Serum cfc-DNA/cfc-RNA Advanced Fractionation Kit 68300-NB 50 preps
Special

1406.75 €
DETAILS   Add to Cart 
Plasma/Serum Total cfc-Nucleic Acid Advanced Purification Kit 68100-NB 50 preps
Special

1222.30 €
DETAILS   Add to Cart 

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