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RNA Methylation Analysis

RNA methylation occurs in different RNA species including tRNA, rRNA, mRNA, tmRNA, snRNA, snoRNA, miRNA, and viral RNA. Different catalytic strategies are employed for RNA methylation by a variety of RNA-methyltransferases. As a post-translational modification, RNA methylation plays a significant role as an epigenetic mechanism. N6-methyladenosine (m6A) is the most common and abundant methylation modification in RNA molecules present in eukaryotes. 5-methylcytosine (5-mC) also commonly occurs in various RNA molecules. Recent data strongly suggest that m6A and 5-mC RNA methylation affects the regulation of various biological processes such as RNA stability and mRNA translation, and that abnormal RNA methylation contributes to etiology of human diseases.


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RNA Methylation Analysis Kits from our partner Epigentek, see links below

*Expires 29 March 2019

EpiQuik m6A RNA Methylation Quantification Kit (Colorimetric)

For absorbance-based quantitation of N6-methyladenosine in RNA in an ELISA-like format.

EpiQuik m6A RNA Methylation Quantification Kit (Fluorometric)

For fluorometric quantitation of N6-methyladenosine (m6A or 6mA) in RNA.

MethylFlash Urine N6-methyladenosine (m6A) Quantification Kit (Colorimetric)

For colorimetric quantitation of m6A in urine using an inhibitory competitive immunoassay method.

Epigenase m6A Demethylase Activity/Inhibition Assay Kit (Colorimetric)

For measuring total m6A demethylase activity/inhibition using nuclear extracts or purified m6A demethylases like FTO and ALKBH5 from a broad range of species.

MethylFlash 5-mC RNA Methylation ELISA Easy Kit (Fluorometric)

For fluorescence-based quantitation of global 5-mC RNA methylation in an ELISA-like format.

Methylamp RNA Bisulfite Conversion Kit

For robust, chemical-based bisulfite treatment of RNA for methylated cytosine analysis.

EpiNext Hi-Fi cDNA Synthesis Kit

For efficient cDNA synthesis from bisulfite-converted RNA and enriched RNA fragments.

EpiNext 5-mC RNA Bisulfite-Seq Easy Kit (Illumina)

For RNA bisulfite conversion, followed by a "post-bisulfite" library preparation process.


MethylFlash Kits

BioCat Epigenetics Research

Use Epigentek's MethylFlash Kits for the quantification of epigenetic parameters.

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