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CRISPR/Cas9 Genome Engineering

CRISPR/Cas9
  • All-in-one Cas9/gRNA plasmids
  • Injection-ready Cas9 mRNA
  • Packaged Cas9 lentivirus
  • AAV-Cas9 vectors
  • Multiplex gRNA cloning kits

The CRISPR/Cas9 system, consisting of a nuclease (Cas9) and a DNA-directed guide RNA (gRNA), allows for sequence-specific cleavage of target sequence containing a protospacer adaptor motif “NGG”. By changing the gRNA target sequence, virtually any gene sequence upstream of a PAM motif can be targeted by the CRISPR/Cas9 system, enabling the possibility of systematic targeting of sequences on a genomic scale.

Selection Guide

MODIFYING ORGANISMS
MODIFYING CELL LINES
PRE-CLINICAL APPLICATIONS
SIMULTANEOUS ENGINEERING
OF MULTIPLE MUTATIONS
ACCESSORIES
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