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Stem Cell Fate Modulators

• High purity
• Structurally verified
• High biological activity

Natural and synthetic small molecules have been shown to be useful chemical tools for controlling and manipulating the fates of cells. A variety of cell-permeable small molecules modulating stem cell differentiation, self-renewal, and reprogramming is offered. For example, Y-27632, a selective Rho kinase (ROCK) inhibitor, prevents apoptosis and enhances the survival and cloning efficiency of dissociated human embryonic stem cells without affecting their pluripotency.
CHIR99021, a highly selective inhibitor of glycogen synthase kinase-3ß (GSK-3ß) has been shown to allow for long-term expansion of murine embryonic stem cells in a chemically-defined medium in conjunction with MEK/MAPK inhibitor PD184352 and fibroblast growth factor receptor (FGFR) inhibitor SU5402.
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Overview of Tools for Stem Cell Research

 

 

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Description Cat# Size Price    
DiscoveryPak Stem Cell Fate Regulator Set I (For sustaining of embryonic stem cell renewal) K852-3-BV Set of 3 modulators 564 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set II (For stem cell self-renewal, differentiation, and reprogramming) K853-8-BV Set of 8 modulators 1056 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set III (For promoting the reprogramming of fibroblasts into induced pluripotent stem cells (iPSCs) K854-3-BV Set of 3 modulators 430 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set IV (For promoting the survival of embryonic stem cells) K855-3-BV Set of 3 modulators 462 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set V (For generating human induced pluripotent stem cells (iPSCs) from primary cells) K865-5-BV Set of 5 modulators 524 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set VI (For self-renewal of stem cells and induced pluripotent stem cells (iPSCs) K866-5-BV Set of 5 Modulators 738 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set VII (For enhancing the reprogramming of primary human cells into induced pluripotent stem cells (iPSCs) K867-10-BV Set of 10 Modulators 943 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set I (1000X), Sterile-Filtered K869-1ML-BV 1 ml 257 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set I (1000X), Sterile-Filtered K869-5ML-BV 5 ml 790 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set I (1000X), Sterile-Filtered K869-set-BV 5 x 1 ml 830 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set II (1000X), Sterile-Filtered K870-1ML-BV 1 ml 257 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set II (1000X), Sterile-Filtered K870-5ML-BV 5 ml 790 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set II (1000X), Sterile-Filtered K870-set-BV 5 x 1 ml 820 € DETAILS   Add to Cart 
StemBoost YPAC Cocktail Set (1000X), Sterile-Filtered K871-1ML-BV 1 ml 308 € DETAILS   Add to Cart 
StemBoost YPAC Cocktail Set (1000X), Sterile-Filtered K871-5ML-BV 5 ml 892 € DETAILS   Add to Cart 
StemBoost YPAC Cocktail Set (1000X), Sterile-Filtered K871-set-BV 5 x 1 ml 933 € DETAILS   Add to Cart 
(Plus Minus) - Bay K 8644 1682-5-BV 5 mg 251 € DETAILS   Add to Cart 
A 83-01 1725-1-BV 1 mg 177 € DETAILS   Add to Cart 
A83-01, Sterile-Filtered EZ-Solution 1989-1-BV 1 ml 287 € DETAILS   Add to Cart 
AM580 2635-1-BV 1 mg 123 € DETAILS   Add to Cart 
AM580 2635-5-BV 5 mg 338 € DETAILS   Add to Cart 
BIO 1673-1-BV 1 mg 162 € DETAILS   Add to Cart 
BIX 01294 1678-25-BV 25 mg 576 € DETAILS   Add to Cart 
BIX 01294 1678-5-BV 5 mg 192 € DETAILS   Add to Cart 
Cancer Cell Stemness Inhibitor, BBI608 2476-25-BV 25 mg 790 € DETAILS   Add to Cart 
Cancer Cell Stemness Inhibitor, BBI608 2476-5-BV 5 mg 235 € DETAILS   Add to Cart 
CD437 2636-25-BV 25 mg 585 € DETAILS   Add to Cart 
CD437 2636-5-BV 5 mg 196 € DETAILS   Add to Cart 
CHIR 99021 1677-25-BV 25 mg 845 € DETAILS   Add to Cart 
CHIR 99021 1677-5-BV 5 mg 308 € DETAILS   Add to Cart 
CHIR99021, Sterile-Filtered EZ-Solution 1991-1-BV 1 ml 333 € DETAILS   Add to Cart 
CI-1040 (PD184352) (MEK Inhibitor) 1585-25-BV 25 mg 892 € DETAILS   Add to Cart 
CI-1040 (PD184352) (MEK Inhibitor) 1585-5-BV 5 mg 364 € DETAILS   Add to Cart 
Cyclopamine 1578-5-BV 5 mg 287 € DETAILS   Add to Cart 
Cyclosporine A 1522-100-BV 100 mg 160 € DETAILS   Add to Cart 
Cyclosporine A 1522-1G-BV 1 g 297 € DETAILS   Add to Cart 
Dexamethasone 1042-10G-BV 10 g 621 € DETAILS   Add to Cart 
Dexamethasone 1042-1G-BV 1 g 177 € DETAILS   Add to Cart 
Dexamethasone (10 mM) 1042-1-BV 1 ml 153 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set IX (VC6TFZ) K888-6-BV 6 modulators 743 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set VIII (VC6T) K887-4-BV 4 modulators 451 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set X K396-2-BV 2 modulators 462 € DETAILS   Add to Cart 
DiscoveryPakNeuronal Cell InductionSmall Molecules Set K892-8-BV 8 modulators 892 € DETAILS   Add to Cart 
EZSolution 8-Br-cAMP, Sterile-filtered B2257-5-BV 5 mg 144 € DETAILS   Add to Cart 
EZSolution ISX9, Sterile-filtered B2240-5-BV 5 mg 215 € DETAILS   Add to Cart 
EZSolution StemRegenin 1, Free base 2643-1-BV 1 mg 153 € DETAILS   Add to Cart 
EZSolution Trichostatin A 2271-1-BV 1 mg 196 € DETAILS   Add to Cart 
FH1 (BRD-K4477) 2732-25-BV 25 mg 544 € DETAILS   Add to Cart 
FH1 (BRD-K4477) 2732-5-BV 5 mg 177 € DETAILS   Add to Cart 
Forskolin 1531-5-BV 5 mg 157 € DETAILS   Add to Cart 
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