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Stem Cell Fate Modulators

• High purity
• Structurally verified
• High biological activity

Natural and synthetic small molecules have been shown to be useful chemical tools for controlling and manipulating the fates of cells. A variety of cell-permeable small molecules modulating stem cell differentiation, self-renewal, and reprogramming is offered. For example, Y-27632, a selective Rho kinase (ROCK) inhibitor, prevents apoptosis and enhances the survival and cloning efficiency of dissociated human embryonic stem cells without affecting their pluripotency.
CHIR99021, a highly selective inhibitor of glycogen synthase kinase-3ß (GSK-3ß) has been shown to allow for long-term expansion of murine embryonic stem cells in a chemically-defined medium in conjunction with MEK/MAPK inhibitor PD184352 and fibroblast growth factor receptor (FGFR) inhibitor SU5402.
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Overview of Tools for Stem Cell Research

 

 

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Description Cat# Size Price    
DiscoveryPak Stem Cell Fate Regulator Set I (For sustaining of embryonic stem cell renewal) K852-3-BV Set of 3 modulators 576 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set II (For stem cell self-renewal, differentiation, and reprogramming) K853-8-BV Set of 8 modulators 1078 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set III (For promoting the reprogramming of fibroblasts into induced pluripotent stem cells (iPSCs) K854-3-BV Set of 3 modulators 439 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set IV (For promoting the survival of embryonic stem cells) K855-3-BV Set of 3 modulators 468 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set V (For generating human induced pluripotent stem cells (iPSCs) from primary cells) K865-5-BV Set of 5 modulators 535 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set VI (For self-renewal of stem cells and induced pluripotent stem cells (iPSCs) K866-5-BV Set of 5 Modulators 753 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set VII (For enhancing the reprogramming of primary human cells into induced pluripotent stem cells (iPSCs) K867-10-BV Set of 10 Modulators 962 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set I (1000X), Sterile-Filtered K869-1ML-BV 1 ml 263 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set I (1000X), Sterile-Filtered K869-5ML-BV 5 ml 806 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set I (1000X), Sterile-Filtered K869-set-BV 5 x 1 ml 847 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set II (1000X), Sterile-Filtered K870-1ML-BV 1 ml 263 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set II (1000X), Sterile-Filtered K870-5ML-BV 5 ml 806 € DETAILS   Add to Cart 
StemBoost Reprogramming Cocktail Set II (1000X), Sterile-Filtered K870-set-BV 5 x 1 ml 837 € DETAILS   Add to Cart 
StemBoost YPAC Cocktail Set (1000X), Sterile-Filtered K871-1ML-BV 1 ml 315 € DETAILS   Add to Cart 
StemBoost YPAC Cocktail Set (1000X), Sterile-Filtered K871-5ML-BV 5 ml 910 € DETAILS   Add to Cart 
StemBoost YPAC Cocktail Set (1000X), Sterile-Filtered K871-set-BV 5 x 1 ml 952 € DETAILS   Add to Cart 
(Plus Minus) - Bay K 8644 1682-5-BV 5 mg 257 € DETAILS   Add to Cart 
A 83-01 1725-1-BV 1 mg 181 € DETAILS   Add to Cart 
A83-01, Sterile-Filtered EZ-Solution 1989-1-BV 1 ml 293 € DETAILS   Add to Cart 
AM580 2635-1-BV 1 mg 126 € DETAILS   Add to Cart 
AM580 2635-5-BV 5 mg 345 € DETAILS   Add to Cart 
BIO 1673-1-BV 1 mg 166 € DETAILS   Add to Cart 
BIX 01294 1678-25-BV 25 mg 588 € DETAILS   Add to Cart 
BIX 01294 1678-5-BV 5 mg 196 € DETAILS   Add to Cart 
Cancer Cell Stemness Inhibitor, BBI608 2476-25-BV 25 mg 806 € DETAILS   Add to Cart 
Cancer Cell Stemness Inhibitor, BBI608 2476-5-BV 5 mg 240 € DETAILS   Add to Cart 
CD437 2636-25-BV 25 mg 597 € DETAILS   Add to Cart 
CD437 2636-5-BV 5 mg 200 € DETAILS   Add to Cart 
CHIR 99021 1677-25-BV 25 mg 874 € DETAILS   Add to Cart 
CHIR 99021 1677-5-BV 5 mg 329 € DETAILS   Add to Cart 
CHIR99021, Sterile-Filtered EZ-Solution 1991-1-BV 1 ml 353 € DETAILS   Add to Cart 
CI-1040 (PD184352) (MEK Inhibitor) 1585-25-BV 25 mg 910 € DETAILS   Add to Cart 
CI-1040 (PD184352) (MEK Inhibitor) 1585-5-BV 5 mg 372 € DETAILS   Add to Cart 
Cyclopamine 1578-5-BV 5 mg 293 € DETAILS   Add to Cart 
Cyclosporine A 1522-100-BV 100 mg 164 € DETAILS   Add to Cart 
Cyclosporine A 1522-1G-BV 1 g 303 € DETAILS   Add to Cart 
Dexamethasone 1042-10G-BV 10 g 657 € DETAILS   Add to Cart 
Dexamethasone 1042-1G-BV 1 g 201 € DETAILS   Add to Cart 
Dexamethasone (10 mM) 1042-1-BV 1 ml 163 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set IX (VC6TFZ) K888-6-BV 6 modulators 758 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set VIII (VC6T) K887-4-BV 4 modulators 461 € DETAILS   Add to Cart 
DiscoveryPak Stem Cell Fate Regulator Set X K396-2-BV 2 modulators 468 € DETAILS   Add to Cart 
DiscoveryPakNeuronal Cell InductionSmall Molecules Set K892-8-BV 8 modulators 910 € DETAILS   Add to Cart 
EZSolution 8-Br-cAMP, Sterile-filtered B2257-5-BV 5 mg 147 € DETAILS   Add to Cart 
EZSolution ISX9, Sterile-filtered B2240-5-BV 5 mg 220 € DETAILS   Add to Cart 
EZSolution StemRegenin 1, Free base 2643-1-BV 1 mg 157 € DETAILS   Add to Cart 
EZSolution Trichostatin A 2271-1-BV 1 mg 200 € DETAILS   Add to Cart 
FH1 (BRD-K4477) 2732-25-BV 25 mg 555 € DETAILS   Add to Cart 
FH1 (BRD-K4477) 2732-5-BV 5 mg 181 € DETAILS   Add to Cart 
Forskolin 1531-5-BV 5 mg 161 € DETAILS   Add to Cart 
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