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Stem Cell related Products

Stem cells are undifferentiated cells that can remain with the capacity to develop into specialized cell types. Specific triggers are needed for a stem cell to develop into a skin, heart, or lung cell, or any of the other cell types with specific functions in the body; otherwise the stem cell maintains itself in a state of long-term self renewal via mitotic division. Due to these unique properties of differentiation and rejuvenation, stem cells are being evaluated for use in cell-based therapies for diseases such as cancer, and neurodegenerative and muscular diseases.
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Pressing questions in this rapidly evolving field concern the internal and external signals for cell differentiation and the specificity of such signals for differentiation into particular cell types. While individual transcription factors and stem cell markers such as OCT4 have been identified, the revolution in stem cell research is identifying hundreds of other genes that either play a critical role in stem cell biology, or are uniquely impacted within the stem cell environment.

BioCat offers comprehensive tools for investigating stem cell differentiation and pluripotency. The Stem Cell Differentiation Reporter System applies cell-specific promoters and a fluorescent reporter for monitoring differentiation in real-time. With the Pluripotency Reporter System you can determine the pluripotent state of stem cells using reporter constructs with pluripotency factor-specific promoters. Expression Vectors for Human and Mouse Pluripotency Factors like C-MYC, KLF4, LIN28, NANOG, OCT4 (POU5F1, OCT3/4), SOX2 enable cellular reprogramming.
Kits for Stem Cell Characterization using the stem cell marker alkaline phosphatase (AP) and for Stem Cell Quantification and Isolation are also available.
To find the antibody for your target of interest, search our extensive collection of Stem Cell Antibodies, including popular targets such as ALDH, OCT4, c-KIT, and NANOG, see link below.
Related Links

Stem Cell Growth and Differentiation Media
Human Stem Cell-related microRNA qRT-PCR Array


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