Mycoplasma Detection, Prevention and Removal
For articles reporting effects of mycoplasma contamination in cell cultures, see below.
Microbiological contamination in cell culture: a potential role for hydrogen peroxide vapour (HPV) , Otter, J A. Cell Biology International Volume: 32 Issue: 2 (2008-02-01) p. 326-327.
Impact of Mycoplasma hyorhinis infection on L-arginine metabolism: differential regulation of the human and murine iNOS gene Biol Chem. 2005 Oct;386(10):1055-63.
Mycoplasma-mediated alterations of in vitro generation and functions of human dendritic cells. J Biomed Sci. 2005;12(1):31-46.
Amyloid-beta peptide degradation in cell cultures by mycoplasma contaminants. Haitian Zhao , BMC Research Notes 2008, 1:38
Production of prostaglandin E2 in monocytes stimulated in vitro by Chlamydia trachomatis, Chlamydophila pneumoniae, and Mycoplasma fermentans. Microb Pathog. 2004 Sep;37(3):155-61.
Falsification of tetrazolium dye (MTT) based cytotoxicity assay results due to mycoplasma contamination of cell cultures. Anticancer Res. 1999 Mar-Apr;19(2A):1245-8.
Because of severe problem of mycoplasma contamination in cell culture, reviewers of scientific journals usually ask for additional data to prove that authors got the data from mycplasma-free conditioned cell culture.
BioCat is pleased to offer kits for the detection of mycoplasma contaminations.