Endothelial Progenitor CellsFor Angiogenesis Studies and Drug Discovery Research
Endothelial Preogenitor Cells (EPC) are a primitive cell type in the endothelial lineage. They are bone marrow derived cells with properties similar to those of embryonic angioblasts. These progenitor not matured cells migrate into the blood stream and are able to differentiate into a variety of mature vascular endothelial cell types.
EPC are used for cell-based antiangiogenic cancer drug screening and are more suitable than specific mature HUVEC and HMVEC.
• Progenitor cells, not terminally differentiated mature endothelial cells such as HUVEC and HMVEC
• Capable of differentiating into specific subtypes of endothelial cells
• Gene expression pattern is similar to that of endothelial cells from tumors
• Specifically migrate to human tumors
• Quantity and functions in the human blood is altered during pathogenesis of a variety of human diseases, such as
- Cancers (e.g. lymphoma, breast cancer, lung cancer, and inoperable heptocellular carcinoma (HCC)
- Vascular diseases (e.g. coronary artery disease (CAD) and acute myocardial infarction)
- Other diseases (e.g. Diabetes Mellitus, Ischemia, Pulmonary hypertension, Cerebral vascular disease, Arthritis, Cutaneous wound healing and skin regeneration)
|Mouse Endothelial Progenitor Cells (EPC), Adult, > 500.000 cryopreserved cells||Z7030031-BC||1 vial||please inquire €||DETAILS||Add to Cart|