Histone methylation is one of the most well characterized and studied epigenetic marks. Methylation can occur at various sites in histone proteins, primarily on lysine and arginine residues. It is modulated by multiple positive and negative regulators, even at a single site, to either activate or repress transcription.
Our partner Epigentek has developed a comprehensive selection of ELISA-like or fluorescence-based kits for the quantification of changes in histone H3 or histone H4 methylation. Multiplex kits for the simultaneous measurement of different histone modification patterns are also available.
*Expires 31 March 2020